An Efficient and Eco-Friendly Procedure for the Synthesis of Hantzsch Ethyl 1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylates Under Mild and Green Conditions

Title: An Efficient and Eco-Friendly Procedure for the Synthesis of Hantzsch Ethyl 1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylates Under Mild and Green Conditions

Volume: 3 Issue: 2

Author(s): Mohammad A. Zolfigol, Peyman Salehi and Maliheh Safaiee

Affiliation:

Keywords: Hantzsch synthesis, 1,4-dihydroyridines, solvent-free conditions, green conditions, ammonium salts, ethyl 1,4-dihydro-2, 6-dimethylpyridine-3, 3,5-dicarboxylate

Abstract: A mixture of ethyl acetoacetate and various aldehydes in the presence of ammonium salts was converted to Hantzsch ethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates under mild and green conditions with good to excellent yields.

Cite this article as:

Zolfigol A. Mohammad, Salehi Peyman and Safaiee Maliheh, An Efficient and Eco-Friendly Procedure for the Synthesis of Hantzsch Ethyl 1,4-Dihydro-2,6-Dimethylpyridine-3,5-Dicarboxylates Under Mild and Green Conditions, Letters in Organic Chemistry 2006; 3 (2) . https://dx.doi.org/10.2174/157017806775224288