Abstract
It is well known that legumes, especially soybeans, are beneficial to health due to the presence of saponins and an abundance of fiber and proteins. Defensins and other related defense proteins with antifungal activity in legumes act against fungi which are human pathogens and also against phytopathogenic fungi. These proteins exhibit HIV-1 reverse transcriptase inhibitory and antitumor activities. Some of these proteins have remarkable stability to proteases, and changes in pH and temperature and are promising therapeutic candidates.
Keywords: Defensins, beans, biocidal proteins, bean seeds, medicinal activity, antifungal, HIV-1 reverse transcriptase inhibitory activity, antitumor activity, phytopathogenic fungi, antitumor activities
Current Medicinal Chemistry
Title: Defensins and Other Biocidal Proteins from Bean Seeds with Medicinal Activities
Volume: 18 Issue: 36
Author(s): T. B. Ng, J. H. Wong and E. F. Fang
Affiliation:
Keywords: Defensins, beans, biocidal proteins, bean seeds, medicinal activity, antifungal, HIV-1 reverse transcriptase inhibitory activity, antitumor activity, phytopathogenic fungi, antitumor activities
Abstract: It is well known that legumes, especially soybeans, are beneficial to health due to the presence of saponins and an abundance of fiber and proteins. Defensins and other related defense proteins with antifungal activity in legumes act against fungi which are human pathogens and also against phytopathogenic fungi. These proteins exhibit HIV-1 reverse transcriptase inhibitory and antitumor activities. Some of these proteins have remarkable stability to proteases, and changes in pH and temperature and are promising therapeutic candidates.
Export Options
About this article
Cite this article as:
B. Ng T., H. Wong J. and F. Fang E., Defensins and Other Biocidal Proteins from Bean Seeds with Medicinal Activities, Current Medicinal Chemistry 2011; 18 (36) . https://dx.doi.org/10.2174/092986711798347306
DOI https://dx.doi.org/10.2174/092986711798347306 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Current Perspective of Natural Alkaloid Carbazole and its Derivatives as Antitumor Agents
Anti-Cancer Agents in Medicinal Chemistry Anticancer Drugs Discovery and Development from Marine Organisms
Current Topics in Medicinal Chemistry Cigarette Smoking, Metabolic Activation and Carcinogenesis
Current Drug Metabolism Compounds From Celastraceae Targeting Cancer Pathways and Their Potential Application in Head and Neck Squamous Cell Carcinoma: A Review
Current Genomics Treatment of GM2 Gangliosidosis in Adult Sandhoff Mice Using an Intravenous Self-Complementary Hexosaminidase Vector
Current Gene Therapy Dysregulation of Neurotrophic and Haematopoietic Growth Factors in Alzheimer’s Disease: From Pathophysiology to Novel Treatment Strategies
Current Alzheimer Research Dietary Supplementation of Curcumin Alleviates NF-κB-dependent Skeletal Muscle Wasting in Rat
Endocrine, Metabolic & Immune Disorders - Drug Targets Experimental and Computational Insights into Bis-indolylmethane Derivatives as Potent Antimicrobial Agents Inhibiting 2,2-dialkylglycine Decarboxylase
Current Enzyme Inhibition 2,3-Dichloroquinoxaline in Cross-coupling Reactions: A Single Substrate, Many Possibilities
Current Organic Chemistry Beyond Stressed Self: Evidence for NKG2D Ligand Expression on Healthy Cells
Current Immunology Reviews (Discontinued) Pharmacological Activity of Natural Non-glycosylated Triterpenes
Mini-Reviews in Organic Chemistry Jaridonin, a Novel Ent-Kaurene Diterpenoid from Isodon rubescens, Inducing Apoptosis via Production of Reactive Oxygen Species in Esophageal Cancer Cells
Current Cancer Drug Targets Delivery of Intracellular-Acting Biologics in Pro-Apoptotic Therapies
Current Pharmaceutical Design Engineered Polymer Nanoplatforms for Targeted Tumor Cells and Controlled Release Cargos to Enhance Cancer Treatment
Current Medicinal Chemistry High Throughput Screening Technology and the Small Molecules Modulating Aging Related Signals
Combinatorial Chemistry & High Throughput Screening Renal Cell Cancer and Positron Emission Tomography- an Evolving Diagnostic and Therapeutic Relationship
Current Medical Imaging Vital Tooth Whitening Techniques. A Literature Review
Current Dentistry Antiviral Treatment of Cytomegalovirus Infection
Infectious Disorders - Drug Targets Biologic Agents in the Treatment of Psoriasis
Recent Patents on Inflammation & Allergy Drug Discovery Mechanisms of Resistance to Chemotherapy in Gastric Cancer
Anti-Cancer Agents in Medicinal Chemistry