Proteome Analysis of Resting Human Neutrophils

Title: Proteome Analysis of Resting Human Neutrophils

Volume: 13 Issue: 5

Author(s): Mariana d. S. Castro, Natan M. de Sa, Renata P. Gadelha, Marcelo V. de Sousa, Carlos A. O. Ricart, Belchor Fontes and Wagner Fontes

Affiliation:

Keywords: Neutrophils, proteome, peptide mass fingerprinting, inflammatory response

Abstract: Neutrophils constitute the first line of host defense against pathogens. In the present study 2-D gel electrophoresis- mass spectrometry technology was employed to analyze the human resting neutrophils proteome. One hundred and two conserved spots were subjected to peptide mass fingerprinting, yielding 22 identifications. Among the identified proteins, nine are related to the inflammatory process, two polypeptides are assigned to metabolic functions and five are classified as structural.

Cite this article as:

Castro d. S. Mariana, de Sa M. Natan, Gadelha P. Renata, de Sousa V. Marcelo, Ricart A. O. Carlos, Fontes Belchor and Fontes Wagner, Proteome Analysis of Resting Human Neutrophils, Protein & Peptide Letters 2006; 13 (5) . https://dx.doi.org/10.2174/092986606776819529