Antioxidative Actions of Statins: Potential Mechanisms for Antiathersclerotic Effects

Title: Antioxidative Actions of Statins: Potential Mechanisms for Antiathersclerotic Effects

Volume: 6 Issue: 5

Author(s): Takanori Watanabe, Kenichi Yasunari and Munehoro Nakamura

Affiliation:

Keywords: Statins, oxidative stress, atherosclerosis, carotid artery, leukocytes, flow cytemetory

Abstract: Inhibitors of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase (statins) are widely used for the prevention of atherosclerotic diseases. The effects of statins on the generation of reactive oxygen species (ROS) by in vitro and in vivo were studied. Administration of statins significantly decreased ROS generation in vitro and in vivo.

Cite this article as:

Watanabe Takanori, Yasunari Kenichi and Nakamura Munehoro, Antioxidative Actions of Statins: Potential Mechanisms for Antiathersclerotic Effects, Mini-Reviews in Medicinal Chemistry 2006; 6 (5) . https://dx.doi.org/10.2174/138955706776876249