Stability and Drug Metabolism Assessed by Electrochemical Methods

Title: Stability and Drug Metabolism Assessed by Electrochemical Methods

Volume: 13 Issue: 8

Author(s): Alejandro Alvarez-Lueje and Soledad Bollo Dragnic

Affiliation:

Keywords: Drug, stability, metabolism, voltammetry, polarography, biosensors, electrochemistry-mass spectrometry

Abstract: This review is focused on the use of the electrochemical techniques, voltammetry and polarography, as well as biosensors, for the study of drug stability. In addition, this review also details the study of drug metabolism by electrochemistry and mass spectrometry. This is used as a tool to mimic drug metabolism and because it is a purely instrumental method, may have advantages over, or be complementary to, the existing biological assays.

Cite this article as:

Alvarez-Lueje Alejandro and Bollo Dragnic Soledad, Stability and Drug Metabolism Assessed by Electrochemical Methods, Combinatorial Chemistry & High Throughput Screening 2010; 13 (8) . https://dx.doi.org/10.2174/138620710791920329