The No-Reflow Phenomenon in the Coronary Circulation

Title: The No-Reflow Phenomenon in the Coronary Circulation

Volume: 7 Issue: 3

Author(s): Thomas J. Kiernan, Nicholas J. Ruggiero II, Juan M. Bernal, Creighton W. Don, Christian Witzke, Gareth D. Kiernan, Roberto J. Cubeddu and Bryan P. Yan

Affiliation:

Abstract: The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries. In this contemporary review we endeavour to discuss the pathophysiology of coronary no-reflow, understand the predictors and describe current pharmacological and mechanical strategies to prevent and treat coronary no-reflow.

Cite this article as:

Kiernan J. Thomas, Ruggiero II J. Nicholas, Bernal M. Juan, Don W. Creighton, Witzke Christian, Kiernan D. Gareth, Cubeddu J. Roberto and Yan P. Bryan, The No-Reflow Phenomenon in the Coronary Circulation, Cardiovascular & Hematological Agents in Medicinal Chemistry 2009; 7 (3) . https://dx.doi.org/10.2174/187152509789105426