Abstract
The cardiac and vascular systems work in coordination by activating various reflex mechanisms based on the body’s needs. These may be during physiological variations or pathophysiological changes seen in disease conditions of varying degrees of severity. This article intends to explain various reflexes involved in the homeostasis of the cardiovascular system and the role of vagus as the key component in all these reflexes. The article also explains the components of the reflex arc, the stimulus and response, and the role of reflex in a few diseases. This article describes 22 different cardiovascular reflexes in detail.
Graphical Abstract
[http://dx.doi.org/10.1161/01.CIR.95.7.1813] [PMID: 9107168]
[http://dx.doi.org/10.1152/jappl.1983.54.4.961] [PMID: 6853303]
[http://dx.doi.org/10.1172/JCI115176] [PMID: 1902491]
[http://dx.doi.org/10.1113/jphysiol.1994.sp019997] [PMID: 8014887]
[http://dx.doi.org/10.1002/ar.23829] [PMID: 29663677]
[http://dx.doi.org/10.1007/s00421-018-3831-1] [PMID: 29497836]
[http://dx.doi.org/10.1007/s10072-013-1420-y]
[http://dx.doi.org/10.1113/expphysiol.2005.032250] [PMID: 16210446]
[http://dx.doi.org/10.1111/j.1440-1681.1989.tb02993.x] [PMID: 2805444]
[http://dx.doi.org/10.1111/j.1440-1681.1989.tb02995.x] [PMID: 2680189]
[http://dx.doi.org/10.1002/cphy.c190038] [PMID: 33577130]
[http://dx.doi.org/10.2170/jjphysiol.38.399] [PMID: 3070104]
[http://dx.doi.org/10.3389/fneur.2019.01411] [PMID: 32038467]
[http://dx.doi.org/10.1016/j.jocn.2007.05.025] [PMID: 18182296]
[http://dx.doi.org/10.1016/0090-3019(88)90140-1] [PMID: 3375974]
[http://dx.doi.org/10.1016/j.clinph.2018.09.010] [PMID: 30453271]
[http://dx.doi.org/10.1213/ANE.0b013e3182312e21] [PMID: 21965361]
[http://dx.doi.org/10.1113/jphysiol.1915.sp001736] [PMID: 16993330]
[http://dx.doi.org/10.1152/ajpheart.00019.2013] [PMID: 23729210]
[http://dx.doi.org/10.1152/physrev.1991.71.3.617] [PMID: 2057525]
[http://dx.doi.org/10.1111/j.1748-1716.1987.tb08126.x] [PMID: 3300168]
[http://dx.doi.org/10.1113/jphysiol.1914.sp001676] [PMID: 16993269]
[http://dx.doi.org/10.1016/0002-9149(79)90217-0] [PMID: 495495]
[PMID: 690924]
[http://dx.doi.org/10.1113/jphysiol.1974.sp010503] [PMID: 4825477]
[PMID: 430392]
[http://dx.doi.org/10.1097/00000542-200305000-00030] [PMID: 12717149]
[http://dx.doi.org/10.1111/j.1749-6632.2001.tb03666.x] [PMID: 11458703]
[http://dx.doi.org/10.1016/S0735-1097(83)80014-X] [PMID: 6826948]
[http://dx.doi.org/10.11648/j.ajim.20200801.15]
[http://dx.doi.org/10.1136/bjsm.37.3.277] [PMID: 12782559]
[http://dx.doi.org/10.2165/00007256-200737040-00028] [PMID: 17465614]
[http://dx.doi.org/10.1016/0033-0620(82)90012-3] [PMID: 6805039]
[http://dx.doi.org/10.2174/1874309901307010016]
[http://dx.doi.org/10.1016/S0079-6123(05)52014-4] [PMID: 16198703]
[http://dx.doi.org/10.2174/1568016043477242] [PMID: 15320796]
[http://dx.doi.org/10.1161/ATVBAHA.107.149740] [PMID: 17881738]
[http://dx.doi.org/10.1152/japplphysiol.01024.2006] [PMID: 17170205]
[http://dx.doi.org/10.1161/01.CIR.90.5.2285] [PMID: 7955185]
[http://dx.doi.org/10.1111/micc.12348] [PMID: 28036147]
[http://dx.doi.org/10.1152/advan.00074.2010] [PMID: 21385995]
[http://dx.doi.org/10.1152/jappl.1992.72.1.288] [PMID: 1537727]
[http://dx.doi.org/10.1161/01.RES.59.5.483] [PMID: 3542277]
[http://dx.doi.org/10.1161/01.RES.17.6.540] [PMID: 5843887]
[PMID: 645874]
[PMID: 464105]
[PMID: 7193981]
[http://dx.doi.org/10.2147/OPTH.S317447] [PMID: 34194223]
[http://dx.doi.org/10.1016/B978-0-12-800421-0.00007-2]
[http://dx.doi.org/10.1007/s00270-022-03337-2] [PMID: 36539513]
[http://dx.doi.org/10.3389/fneur.2017.00052] [PMID: 28270794]
[http://dx.doi.org/10.1136/emermed-2011-200877] [PMID: 22389355]
[http://dx.doi.org/10.1016/0031-9384(86)90018-1] [PMID: 3961003]
[http://dx.doi.org/10.1111/apha.12639] [PMID: 26662857]
[http://dx.doi.org/10.1016/S0140-6736(15)61485-4] [PMID: 26314489]
[http://dx.doi.org/10.1016/j.jcin.2017.05.063] [PMID: 28797428]
[http://dx.doi.org/10.1016/j.jacc.2014.10.031] [PMID: 25593060]
[http://dx.doi.org/10.1152/physiol.00037.2013] [PMID: 24583769]
[http://dx.doi.org/10.1161/CIRCULATIONAHA.108.843938] [PMID: 19752352]
[http://dx.doi.org/10.3389/fmed.2021.769437] [PMID: 35186966]
[PMID: 14563598]
[http://dx.doi.org/10.1161/CIRCULATIONAHA.110.970988] [PMID: 20956224]
[http://dx.doi.org/10.1016/j.eupc.2004.08.008] [PMID: 15519256]
[http://dx.doi.org/10.2459/JCM.0000000000000544] [PMID: 28737621]
[http://dx.doi.org/10.1007/s11886-012-0265-y] [PMID: 22528555]
[http://dx.doi.org/10.1093/eurheartjsupp/suac031] [PMID: 35991620]
[http://dx.doi.org/10.1093/eurheartj/ehq391] [PMID: 21030409]
[http://dx.doi.org/10.1161/01.CIR.95.11.2573]
[http://dx.doi.org/10.1111/j.1540-8159.2006.00340.x] [PMID: 16606401]
[http://dx.doi.org/10.1016/j.eupc.2004.10.003]
[http://dx.doi.org/10.1016/j.hrcr.2018.07.018] [PMID: 30479951]