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Current Social Sciences

Editor-in-Chief

ISSN (Print): 2772-316X
ISSN (Online): 2772-3178

Editorial

Cannabidiol (CBD) Listed as a Drug of Abuse by the Italian Health Ministry: Expert Opinion

In Press, (this is not the final "Version of Record"). Available online 26 April, 2024
Author(s): Carla Comacchio, Matteo Balestrieri and Marco Colizzi*
Published on: 26 April, 2024

Article ID: e260424229433

DOI: 10.2174/012772316X295557240417104307

Price: $95

Abstract

In August 2023, the Italian Health Ministry listed cannabidiol (CBD) as a drug of abuse. This rekindled the debate on the medical and non-medical use of cannabis. The most discussed topics are risks related to the use of cannabis, the decriminalization/legalization of recreational cannabis, and use of cannabis-based drugs for medical purposes. The decision to include CBD in the “Unique Text for drugs of abuse” (DPR.309/1990), along with the already included main psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC), is not particularly relevant to such ongoing discussions. Even when it comes to cannabis-based drugs for medical purposes, such a decision will have a minimum impact on CBD-based medical prescriptions. Instead, a high economic impact is expected on CBD-based products sold online or in specific shops, including the so-called “cannabis-light”, formally sold as a “technological product” for collection purposes but used as over-the-counter drugs for the treatment of several medical conditions. Cannabis-light products have reduced regular drug consumption by about 10%. Also, they are not entirely safe, as the actual content of THC may significantly differ from the one stated, carrying unexpected health risks. Further, CBD is likely not a drug with addictive potential; however, its uncontrolled use for medical purposes needs to be regulated as the court battles are ongoing.

[1]
Italian Health Ministry. Law decree., Available from: https://www.gazzettaufficiale.it/eli/id/2023/08/21/23A04729/SG
[2]
Italian Health Ministry. Law decree, Available from: https://www.gazzettaufficiale.it/eli/id/2020/10/15/20A05476/sg
[3]
Colizzi, M.; Bhattacharyya, S. Neurocognitive effects of cannabis: Lessons learned from human experimental studies. Prog. Brain Res., 2018, 242, 179-216.
[http://dx.doi.org/10.1016/bs.pbr.2018.08.010] [PMID: 30471680]
[4]
Wright, S.; Metts, J. Recreational cannabinoid use: The hazards behind the “high”. J. Fam. Pract., 2016, 65(11), 770-779.
[PMID: 28087865]
[5]
Colizzi, M.; Ruggeri, M.; Bhattacharyya, S. Unraveling the intoxicating and therapeutic effects of cannabis ingredients on psychosis and cognition. Front. Psychol., 2020, 11, 833.
[http://dx.doi.org/10.3389/fpsyg.2020.00833] [PMID: 32528345]
[6]
Connor, J.P.; Stjepanović, D.; Le Foll, B.; Hoch, E.; Budney, A.J.; Hall, W.D. Cannabis use and cannabis use disorder. Nat. Rev. Dis. Primers, 2021, 7(1), 16.
[http://dx.doi.org/10.1038/s41572-021-00247-4] [PMID: 33627670]
[7]
Assanangkornchai, S.; Kalayasiri, R.; Ratta-apha, W.; Tanaree, A. Effects of cannabis legalization on the use of cannabis and other substances. Curr. Opin. Psychiatry, 2023, 36(4), 283-289.
[http://dx.doi.org/10.1097/YCO.0000000000000868] [PMID: 37185310]
[8]
McGinty, E.E.; Niederdeppe, J.; Heley, K.; Barry, C.L. Public perceptions of arguments supporting and opposing recreational marijuana legalization. Prev. Med., 2017, 99, 80-86.
[http://dx.doi.org/10.1016/j.ypmed.2017.01.024] [PMID: 28189806]
[9]
(a) World Health Organization (WHO) Drugs. Drugs (psychoactive): Cannabidiol (compound of cannabis). https://www.who.int/news-room/questions-and-answers/item/cannabidiol-(compound-of-cannabis)#:~:text=It%20has%20been%20widely%20reported,compounds%20of%20the%20cannabis%20plant;
(b) Carrieri, V.; Madio, L.; Principe, F. Do-it-yourself medicine? the impact of light cannabis liberalization on prescription drugs. J. Health Econ., 2020, 74, 102371.
[http://dx.doi.org/10.1016/j.jhealeco.2020.102371] [PMID: 32920244]
[10]
Pavlovic, R.; Nenna, G.; Calvi, L.; Panseri, S.; Borgonovo, G.; Giupponi, L.; Cannazza, G.; Giorgi, A. Quality traits of “cannabidiol oils”: Cannabinoids content, terpene fingerprint and oxidation stability of European commercially available preparations. Molecules, 2018, 23(5), 1230.
[http://dx.doi.org/10.3390/molecules23051230] [PMID: 29783790]
[11]
Italian Health Ministry. Recommendations for the doctor prescribing the herbal substance cannabis FM2 inflorescences., Available from: https://www.salute.gov.it/imgs/C_17_pagineAree_4589_listaFile_itemName_2_file.pdf

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