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Systematic Review Article

Beneficial Effects of Spirulina on Brain Health: A Systematic Review

In Press, (this is not the final "Version of Record"). Available online 12 January, 2024
Author(s): Shivendra Kumar*, Sunam Saha, Kuldeep Singh, Talever Singh, Avinash Kumar Mishra, Braj Nandan Dubey and Shubham Singh
Published on: 12 January, 2024

Article ID: e120124225622

DOI: 10.2174/0126668629269256231222092721

Price: $95

Abstract

Background: This review provides a concise overview of existing scientific research concerning the potential advantages of incorporating spirulina, a blue-green algae, into one's diet to promote brain health. The substantial nutritional composition and associated health benefits of algae have drawn significant interest.

Methods: Numerous studies have illuminated the neuroprotective characteristics of spirulina, contributing to its positive influence on brain functionality. Primarily, spirulina boasts antioxi-dants, like phycocyanin and beta-carotene, that effectively counter oxidative stress and curb in-flammation within the brain. This is particularly significant as these factors play roles in the ad-vancement of neurodegenerative conditions like Parkinson's and Alzheimer's disease. Additional-ly, spirulina has demonstrated the capacity to enhance cognitive capabilities and enrich memory and learning aptitudes.

Results: Animal-based investigations have revealed that introducing spirulina can bolster spatial learning and memory, as well as guard against cognitive decline linked to aging. Research has in-dicated its potential in shielding against neurotoxins, encompassing heavy metals and specific en-vironmental pollutants. Its potential to neutralize heavy metals and counteract free radicals con-tributes to these protective effects, potentially thwarting neuronal harm.

Conclusion: In conclusion, the extant scientific literature proposes that spirulina integration can elicit advantageous outcomes for brain health. Its antioxidative, neuroprotective, cognitive-enhancing, and mood-regulating properties present a promising avenue for bolstering brain health and potentially diminishing the susceptibility to neurodegenerative ailments. Nonetheless, further research, notably well-designed human clinical trials, is imperative to ascertain the optimal dos-ing, duration, and enduring consequences of spirulina supplementation concerning brain health.

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