Abstract
Background: Among the various statistical measures, Root Mean Square Error (RMSE), Mean absolute Percentage Error (MAPE), and R-squared (Coefficient of determination) are the most widely used methods. The significance of the R square approach in the medical field was extensively discussed in the current review. Furthermore, we compared a number of statistical metrics for potential applications in the treatment of various disorders. In addition, the pertinent patents of R square for the consequences of testosterone and the enzymes aspartate dehydrogenase (AST) and alanine transaminase (ALT) on Polycystic Ovary Syndrome (PCOS) treated patients have been developed.
Method: We study in this paper the detailed comparative study on the biological system using RMSE, MAPE, and Squared, which consists of 29 PCOS-influenced women against 20 healthy women and followed by the obesity verification model over the Sprague Dawley rats.
Results: R Square provides the best results among all mathematical regression analytical methods in PCOS-influenced patients.
Conclusion: In this study, we provide the strong conclusion that aspartate dehydrogenase (AST) with testosterone treated on PCOS influenced women to have a greater chance of getting affected by Non-alcoholic fatty liver disease (NAFLD) rather than alanine transaminase (ALT) with testosterone- treated patients. Furthermore, this study extends their mathematical regression analysis through R squared for the obesity verification over rat model. It confirms that letrozole-treated rats are inhibited in obese compared with control rats, which results in a chance of NAFLD. Therefore, AST combined with testosterone creates a major chance for liver dysfunction.
[http://dx.doi.org/10.1111/jcmm.16205] [PMID: 33369146]
[http://dx.doi.org/10.1002/9781118625590]
2021 [http://dx.doi.org/10.7717/peerj-cs.623] [PMID: 34307865]
[http://dx.doi.org/10.1088/1757-899X/324/1/012049]
[http://dx.doi.org/10.1016/j.ins.2021.11.036]
[http://dx.doi.org/10.1016/j.neucom.2015.12.114]
[http://dx.doi.org/10.3354/cr030079]
[http://dx.doi.org/10.4158/EP.11.5.319] [PMID: 16191492]
2020 [http://dx.doi.org/10.1136/bmjgast-2019-000352] [PMID: 32784205]
[http://dx.doi.org/10.2147/DMSO.S362424] [PMID: 35494531]
[http://dx.doi.org/10.1007/s00210-020-01809-1]
2020 [http://dx.doi.org/10.1016/j.jsbmb.2020.105752] [PMID: 32991990]
[http://dx.doi.org/10.1016/j.lfs.2017.10.020] [PMID: 29055801]
[http://dx.doi.org/10.1016/S0304-4076(96)01818-0]
[http://dx.doi.org/10.1002/0470013192.bsa526]
[http://dx.doi.org/10.1080/00031305.2018.1549100]