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Coronaviruses

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ISSN (Print): 2666-7967
ISSN (Online): 2666-7975

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Letter to the Editor

Explaining Why Africa had Much Lower COVID-19 Fatalities Per Million than Europe and North America

Author(s): Alberto Boretti*

Volume 4, Issue 2, 2023

Published on: 22 August, 2023

Article ID: e070723218560 Pages: 4

DOI: 10.2174/2666796704666230707154746

Price: $65

Abstract

This letter aims to explain the observed difference between COVID-19 fatalities in Europe and America compared to Africa. At present (May 3, 2023), the cumulative number of COVID-19 fatalities per million people has been 3,093 in South America, 2,761 in Europe, and 2,662 in North America. In particular, the United States and the United Kingdom had 3,323 and 3,320, respectively. With fewer opportunities to practice social distancing or hygiene and much more limited access to health care, Africa only had 181 fatalities per million. The better performances of Africa have been ascribed to the positive effects of reduced hygiene, increased biome diversity, lack of masking mandates and restrictions, better access to antivirals, a younger population, and lower vaccination rates, which all may have contributed to the better performances of Africa compared to Europe and North America against COVID-19.

Graphical Abstract

[1]
Our World in Data, COVID-19 Data Explorer. Available from: ourworldindata.org/explorers/coronavirus-data-explorer
[2]
Kids PLN. Kids and COVID: why young immune systems are still on top. Nature 2021; 597: 166-8.
[http://dx.doi.org/10.1038/d41586-021-02423-8] [PMID: 34493845]
[3]
Parker W, Sarafian JT, Broverman SA, Laman JD. Between a hygiene rock and a hygienic hard place. Evol Med Public Health 2021; 9(1): 120-30.
[http://dx.doi.org/10.1093/emph/eoab006] [PMID: 33732461]
[4]
Strachan DP. Hay fever, hygiene, and household size. BMJ 1989; 299(6710): 1259-60.
[http://dx.doi.org/10.1136/bmj.299.6710.1259] [PMID: 2513902]
[5]
COVID-19 treatment studies, COVID-19 early treatment: Realtime analysis of 2,801 studies. Available from: c19early.com/
[6]
Boretti A. Analysis of the performances of the covid-19 therapeutic approaches in the United Arab Emirates. Signa Vitae 2021; 17(3): 256-63.
[7]
Boretti A. Pharmacotherapy for COVID-19 infection in the countries of the Cooperation Council for the Arab States. J Taibah Univ Med Sci 2021; 16(5): 794-7.
[http://dx.doi.org/10.1016/j.jtumed.2021.08.005] [PMID: 34518765]
[8]
Guerrero R, Bravo LE, Muñoz E, Ardila EKG, Guerrero E. COVID-19: The ivermectin African enigma. Colomb Med 2020; 51(4): e2014613.
[PMID: 33795896]
[9]
Bryant A, Lawrie TA, Dowswell T, et al. Ivermectin for prevention and treatment of COVID-19 infection: A systematic review, meta-analysis, and trial sequential analysis to inform clinical guidelines. Am J Ther 2021; 28(4): e434-60.
[http://dx.doi.org/10.1097/MJT.0000000000001402] [PMID: 34145166]
[10]
Boretti A. Zinc augments the antiviral potential of HCQ/CQ and ivermectin to reduce the risks of more serious outcomes from COVID-19 infection. J Trace Elem Med Biol 2022; 71: 126954.
[http://dx.doi.org/10.1016/j.jtemb.2022.126954] [PMID: 35190326]
[11]
Fögen Z. The foegen effect. Medicine 2022; 101(7): e28924-4.
[http://dx.doi.org/10.1097/MD.0000000000028924] [PMID: 35363218]
[12]
Bundgaard H, Bundgaard JS, Raaschou-Pedersen DET, et al. Effectiveness of adding a mask recommendation to other public health measures to prevent SARS-CoV-2 infection in danish mask wearers: A randomized controlled trial. Ann Intern Med 2021; 174(3): 335-43.
[http://dx.doi.org/10.7326/M20-6817]
[13]
MacIntyre CR, Seale H, Dung TC, et al. A cluster randomised trial of cloth masks compared with medical masks in healthcare workers. BMJ Open 2015; 5(4): e006577.
[http://dx.doi.org/10.1136/bmjopen-2014-006577] [PMID: 25903751]
[14]
Boretti A. Efficacy of generalized face masking mandates. Health Serv Res Manag Epidemiol 2021; 8.
[http://dx.doi.org/10.1177/23333928211058023] [PMID: 34778494]
[15]
Boretti A. After less than 2 months, the simulations that drove the world to strict lockdown appear to be wrong, the same of the policies they generated. Health Serv Res Manag Epidemiol 2020; 7.
[http://dx.doi.org/10.1177/2333392820932324] [PMID: 32596417]
[16]
Boretti A. COVID-19 outbreak in victoria, australia update august 1, 2020. Health Serv Res Manag Epidemiol 2020; 7.
[http://dx.doi.org/10.1177/2333392820960350] [PMID: 33102626]
[17]
Boretti A. Scientists are more in favor of COVID-19 protection than restrictions. Ethics Med Public Health 2021; 16: 100627.
[http://dx.doi.org/10.1016/j.jemep.2021.100627] [PMID: 33469561]
[18]
Hachmann NP, Miller J, Collier AY, et al. Neutralization escape by SARS-CoV-2 Omicron subvariants BA. 2.12. 1, BA. 4, and BA. 5. N Engl J Med 2022; 387(1): 86-8.
[http://dx.doi.org/10.1056/NEJMc2206576] [PMID: 35731894]
[19]
Boretti A, Al Zubaidy S. COVID-19 vaccinated and positive rate of infection in Israel and the United Arab Emirates. Dr Sulaiman Al Habib Medical Journal 2021; 3(2): 78-82.
[http://dx.doi.org/10.2991/dsahmj.k.210427.001]
[20]
Boretti A. A higher number of COVID-19 cases and fatalities in Israel phased with the start of the mass vaccination. Health Serv Res Manag Epidemiol 2021; 8.
[http://dx.doi.org/10.1177/23333928211005867] [PMID: 33855127]
[21]
Boekel L, Kummer LY, van Dam KPJ, et al. Adverse events after first COVID-19 vaccination in patients with autoimmune diseases. Lancet Rheumatol 2021; 3(8): e542-5.
[http://dx.doi.org/10.1016/S2665-9913(21)00181-8] [PMID: 34179831]
[22]
Diaz GA, Parsons GT, Gering SK, Meier AR, Hutchinson IV, Robicsek A. Myocarditis and pericarditis after vaccination for COVID-19. JAMA 2021; 326(12): 1210-2.
[http://dx.doi.org/10.1001/jama.2021.13443] [PMID: 34347001]
[23]
Stein C, Nassereldine H, Sorensen RJD, et al. Past SARS-CoV-2 infection protection against re-infection: A systematic review and meta-analysis. Lancet 2023; 401(10379): 833-42.
[http://dx.doi.org/10.1016/S0140-6736(22)02465-5] [PMID: 36930674]
[24]
Adams J, MacKenzie MJ, Amegah AK, et al. The conundrum of low COVID-19 mortality burden in sub-Saharan Africa: myth or reality? Glob Health Sci Pract 2021; 9(3): 433-43.
[http://dx.doi.org/10.9745/GHSP-D-21-00172] [PMID: 34593571]
[25]
Boretti A. The use of antivirals against COVID-19 infection will reduce the number of fatalities in Australia. Coronaviruses 2023; 4.
[http://dx.doi.org/10.2174/2666796704666230228105723]
[26]
Boretti A. Western Countries have shown poorer rather than better performance against COVID-19. Dr Sulaiman Al Habib Medical Journal 2022; 4(4): 209-11.
[http://dx.doi.org/10.1007/s44229-022-00022-x]
[27]
Wachira LJ, Arena R, Sallis JF, et al. Why are COVID-19 effects less severe in Sub-Saharan Africa? Moving more and sitting less may be a primary reason. Prog Cardiovasc Dis 2022; 71: 103-5.
[http://dx.doi.org/10.1016/j.pcad.2022.04.012] [PMID: 35487264]
[28]
Bwire G, Ario AR, Eyu P, et al. The COVID-19 pandemic in the African continent. BMC Med 2022; 20(1): 167.
[http://dx.doi.org/10.1186/s12916-022-02367-4] [PMID: 35501853]
[29]
Bepouka B, Mayasi N, Mandina M, et al. Risk factors for mortality in COVID-19 patients in sub-Saharan Africa: A systematic review and meta-analysis. PLoS One 2022; 17(10): e0276008.
[http://dx.doi.org/10.1371/journal.pone.0276008] [PMID: 36251715]
[30]
Siewe N, Yakubu AA. Hybrid discrete-time-continuous-time models and a SARS CoV-2 mystery: Sub-Saharan Africa’s low SARS CoV-2 disease burden. J Math Biol 2023; 86(6): 91.
[http://dx.doi.org/10.1007/s00285-023-01923-7] [PMID: 37149541]

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