Abstract
Background: I-131 uptake in the breast could be occasionally observed in differentiated thyroid cancer who received I-131 scintigraphy or therapy. Herein, we report a postpartum patient with papillary thyroid cancer with breast uptake who received I-131 therapy.
Case Report: A 33-year-old postpartum woman with thyroid cancer received 120mCi(4440MBq) I- 131 therapy 5 weeks after she ceased to breastfeed. The second day after ingestion of I-131, wholebody scintigraphy demonstrated asymmetric and marked uptake in bilateral breasts. The radiation dose of I-131 in the lactating breast would decrease rapidly by reducing the activity of breasts and expressing breast milk with an electric pump once daily.
Results: The sixth day after administration, scintigraphy demonstrated weak uptake in bilateral breasts.
Conclusion: Physiologic I-131 uptake in the breast could occur in a postpartum woman with thyroid cancer who received I-131 therapy. In this patient, we find that the radiation dose of I-131 accumulated in the lactating breast would decrease rapidly through reducing the activity of breasts and expressing breast milk with an electric pump, which may be a better choice for the postpartum patient who was not given lactation-inhibiting medications and had I-131 therapy.
Graphical Abstract
[PMID: 12215558]
[http://dx.doi.org/10.1677/erc.1.01143] [PMID: 16954431]
[http://dx.doi.org/10.1530/eje.1.02257] [PMID: 16990649]
[http://dx.doi.org/10.5772/1257]
[PMID: 13009898]
[http://dx.doi.org/10.1210/jc.85.8.2936] [PMID: 10946907]
[http://dx.doi.org/10.1038/78630] [PMID: 10932223]
[http://dx.doi.org/10.1038/35021173] [PMID: 10963582]
[http://dx.doi.org/10.1007/BF00285581] [PMID: 7957345]
[PMID: 23133823]
[http://dx.doi.org/10.1210/jc.2011-2803] [PMID: 22869843]
[http://dx.doi.org/10.1016/j.crad.2009.02.014] [PMID: 19520222]
[http://dx.doi.org/10.1097/00003072-199803000-00011] [PMID: 9509935]
[http://dx.doi.org/10.1097/01.rlu.0000242600.23386.1a] [PMID: 17053384]
[http://dx.doi.org/10.1097/01.rlu.0000132953.07351.65] [PMID: 15249829]
[http://dx.doi.org/10.1258/jrsm.2008.080040] [PMID: 18515780]
[http://dx.doi.org/10.1097/RLU.0b013e318233639d] [PMID: 22310272]
[PMID: 8543996]
[http://dx.doi.org/10.1089/105072503322021205] [PMID: 12855021]
[PMID: 7441790]
[http://dx.doi.org/10.3109/02841869409098381] [PMID: 8037794]
[PMID: 9608866]
[http://dx.doi.org/10.1016/j.bbrc.2006.08.170] [PMID: 16982034]
[http://dx.doi.org/10.1158/1078-0432.CCR-04-0074] [PMID: 15240514]
[http://dx.doi.org/10.1007/978-1-4684-0796-9_20] [PMID: 343535]
[http://dx.doi.org/10.1667/0033-7587(2002)158[0220:REOBCR]2.0.CO;2] [PMID: 12105993]
[http://dx.doi.org/10.1097/00008469-200206000-00006] [PMID: 12131656]