Generic placeholder image

Current Cardiology Reviews

Editor-in-Chief

ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

General Review Article

Paradoxical Septal Motion after Uncomplicated Cardiac Surgery: A Consequence of Altered Regional Right Ventricular Contractile Patterns

Author(s): Alfred Stanley, Constantine Athanasuleas* and Navin Nanda

Volume 18, Issue 4, 2022

Published on: 28 March, 2022

Article ID: e060122200068 Pages: 9

DOI: 10.2174/1573403X18666220106115117

open access plus

Abstract

Paroxysmal interventricular septal motion (PSM) is the movement of the septum toward the right ventricle (RV) during cardiac systole. It occurs frequently after uncomplicated cardiac surgery (CS), including coronary bypass (on-pump and off-pump), valve repair or replacement, and with all types of incisions (sternotomy or mini-thoracotomy). It sometimes resolves quickly but may persist for months or become permanent. Global RV systolic function, stroke volume and ejection fraction remain normal after uncomplicated CS, but regional contractile patterns are altered. There is a decrease in longitudinal shortening but an increase in transverse shortening in the endocardial and epicardial right ventricular muscle fibers, respectively. PSM is a secondary event as there is no loss of septal perfusion or thickening. The increased RV transverse shortening (free wall to septal fibers) may modify septal movement resulting in PSM that compensates for the reduced RV longitudinal shortening, thus preserving normal global right ventricular function.

Keywords: Paroxysmal septal motion, right ventricular systolic dysfunction, tricuspid annular plane systolic excursion, tricuspid annular systolic velocity, ventricular interdependence, cardiac systole.

Graphical Abstract

[1]
Burggraf GW, Craige E. Echocardiographic studies of left ventricular wall motion and dimensions after valvular heart surgery. Am J Cardiol 1975; 35(4): 473-80.
[http://dx.doi.org/10.1016/0002-9149(75)90829-2] [PMID: 1119397]
[2]
Force T, Bloomfield P, O’Boyle JE, et al. Quantitative two-dimensional echocardiographic analysis of motion and thickening of the interventricular septum after cardiac surgery. Circulation 1983; 68(5): 1013-20.
[http://dx.doi.org/10.1161/01.CIR.68.5.1013] [PMID: 6311455]
[3]
Lehmann KG, Lee FA, McKenzie WB, et al. Onset of altered interventricular septal motion during cardiac surgery. Assessment by continuous intraoperative transesophageal echocardiography. Circulation 1990; 82(4): 1325-34.
[http://dx.doi.org/10.1161/01.CIR.82.4.1325] [PMID: 2401066]
[4]
Reynolds HR, Tunick PA, Grossi EA, Dilmanian H, Colvin SB, Kronzon I. Paradoxical septal motion after cardiac surgery: A review of 3,292 cases. Clin Cardiol 2007; 30(12): 621-3.
[http://dx.doi.org/10.1002/clc.20201] [PMID: 18069678]
[5]
Schroeder E, Marchandise B, Schoevaerdts JC, Kremer R. Paradoxical ventricular septal motion after cardiac surgery. Analysis of M-mode echocardiograms and follow-up in 324 patients. Acta Cardiol 1985; 40(3): 315-24.
[PMID: 3875201]
[6]
Grines CL, Bashore TM, Boudoulas H, Olson S, Shafer P, Wooley CF. Functional abnormalities in isolated left bundle branch block. The effect of interventricular asynchrony. Circulation 1989; 79(4): 845-53.
[http://dx.doi.org/10.1161/01.CIR.79.4.845] [PMID: 2924415]
[7]
Roeleveld RJ, Marcus JT, Faes TJ, et al. Interventricular septal configuration at mr imaging and pulmonary arterial pressure in pulmonary hypertension. Radiology 2005; 234(3): 710-7.
[http://dx.doi.org/10.1148/radiol.2343040151] [PMID: 15634939]
[8]
Ryan T, Petrovic O, Dillon JC, Feigenbaum H, Conley MJ, Armstrong WF. An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol 1985; 5(4): 918-27.
[http://dx.doi.org/10.1016/S0735-1097(85)80433-2] [PMID: 3973294]
[9]
Voelkel AG, Pietro DA, Folland ED, Fisher ML, Parisi AF. Echocardiographic features of constrictive pericarditis. Circulation 1978; 58(5): 871-5.
[http://dx.doi.org/10.1161/01.CIR.58.5.871] [PMID: 699252]
[10]
Weyman AE, Wann S, Feigenbaum H, Dillon JC. Mechanism of abnormal septal motion in patients with right ventricular volume overload: A cross-sectional echocardiographic study. Circulation 1976; 54(2): 179-86.
[http://dx.doi.org/10.1161/01.CIR.54.2.179] [PMID: 939018]
[11]
Roshanali F, Yousefnia MA, Mandegar MH, Rayatzadeh H, Alinejad S. Decreased right ventricular function after coronary artery bypass grafting. Tex Heart Inst J 2008; 35(3): 250-5.
[PMID: 18941594]
[12]
Kang MK, Chang HJ, Cho IJ, et al. Echocardiographic investigation of the mechanism underlying abnormal interventricular septal motion after open heart surgery. J Cardiovasc Ultrasound 2014; 22(1): 8-13.
[http://dx.doi.org/10.4250/jcu.2014.22.1.8] [PMID: 24753803]
[13]
Hedman A, Alam M, Zuber E, Nordlander R, Samad BA. Decreased right ventricular function after coronary artery bypass grafting and its relation to exercise capacity: A tricuspid annular motion-based study. J Am Soc Echocardiogr 2004; 17(2): 126-31.
[http://dx.doi.org/10.1016/j.echo.2003.10.023] [PMID: 14752486]
[14]
Eslami B, Roitman D, Karp RB, Sheffield LT. The echocardiogram after pericardiectomy. Jpn Heart J 1979; 20(1): 1-5.
[http://dx.doi.org/10.1536/ihj.20.1] [PMID: 449039]
[15]
Unsworth B, Casula RP, Kyriacou AA, et al. The right ventricular annular velocity reduction caused by coronary artery bypass graft surgery occurs at the moment of pericardial incision. Am Heart J 2010; 159(2): 314-22.
[http://dx.doi.org/10.1016/j.ahj.2009.11.013] [PMID: 20152232]
[16]
Righetti A, Crawford MH, O’rourke RA, Schelbert H, Daily PO, Ross J Jr. Interventricular septal motion and left ventricular function after coronary bypass surgery: Evaluation with echocardiography and radionuclide angiography. Am J Cardiol 1977; 39(3): 372-7.
[http://dx.doi.org/10.1016/S0002-9149(77)80091-X] [PMID: 139103]
[17]
Feneley M, Kearney L, Farnsworth A, Shanahan M, Chang V. Mechanisms of the development and resolution of paradoxical interventricular septal motion after uncomplicated cardiac surgery. Am Heart J 1987; 114(1 Pt 1): 106-14.
[http://dx.doi.org/10.1016/0002-8703(87)90314-0] [PMID: 3496774]
[18]
Waggoner AD, Shah AA, Schuessler JS, et al. Effect of cardiac surgery on ventricular septal motion: Assessment by intraoperative echocardiography and cross-sectional two-dimensional echocardiography. Am Heart J 1982; 104(6): 1271-8.
[http://dx.doi.org/10.1016/0002-8703(82)90156-9] [PMID: 7148645]
[19]
Joshi SB, Salah AK, Mendoza DD, Goldstein SA, Fuisz AR, Lindsay J. Mechanism of paradoxical ventricular septal motion after coronary artery bypass grafting. Am J Cardiol 2009; 103(2): 212-5.
[http://dx.doi.org/10.1016/j.amjcard.2008.08.067] [PMID: 19121438]
[20]
Buckberg G, Athanasuleas C, Saleh S. Septal myocardial protection during cardiac surgery for prevention of right ventricular dysfunction. Anadolu Kardiyol Derg 2008; 8(Suppl. 2): 108-16.
[PMID: 19028643]
[21]
Choi SH, Choi SI, Chun EJ, et al. Abnormal motion of the interventricular septum after coronary artery bypass graft surgery: Comprehensive evaluation with MR imaging. Korean J Radiol 2010; 11(6): 627-31.
[http://dx.doi.org/10.3348/kjr.2010.11.6.627] [PMID: 21076588]
[22]
Chouraqui P, Rabinowitz B, Livschitz S, Horoszowsky D, Kaplinsky E, Smolinsky A. Effects of antegrade versus combined antegrade/retrograde cardioplegia on postoperative septal wall motion in patients undergoing open heart surgery. Cardiology 1997; 88(6): 526-9.
[http://dx.doi.org/10.1159/000177403] [PMID: 9397306]
[23]
Giubbini R, Rossini P, Bertagna F, et al. Value of gated SPECT in the analysis of regional wall motion of the interventricular septum after coronary artery bypass grafting. Eur J Nucl Med Mol Imaging 2004; 31(10): 1371-7.
[http://dx.doi.org/10.1007/s00259-004-1569-y] [PMID: 15221295]
[24]
Ozdemir S, Yener AÜ, Barutcu A, Tan YZ, Çelik F. The assessment of septal wall motion in patients undergoing CABG by myocardial perfusion-gated SPECT. Nucl Med Commun 2015; 36(7): 738-46.
[http://dx.doi.org/10.1097/MNM.0000000000000309] [PMID: 25816362]
[25]
Akins CW, Boucher CA, Pohost GM. Preservation of interventricular septal function in patients having coronary artery bypass grafts without cardiopulmonary bypass. Am Heart J 1984; 107(2): 304-9.
[http://dx.doi.org/10.1016/0002-8703(84)90379-X] [PMID: 6607664]
[26]
Wranne B, Pinto FJ, Siegel LC, Miller DC, Schnittger I. Abnormal postoperative interventricular motion: New intraoperative transesophageal echocardiographic evidence supports a novel hypothesis. Am Heart J 1993; 126(1): 161-7.
[http://dx.doi.org/10.1016/S0002-8703(07)80024-X] [PMID: 8322660]
[27]
Jennings RB, Reimer KA. The cell biology of acute myocardial ischemia. Annu Rev Med 1991; 42: 225-46.
[http://dx.doi.org/10.1146/annurev.me.42.020191.001301] [PMID: 2035969]
[28]
Turer AT, Hill JA. Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy. Am J Cardiol 2010; 106(3): 360-8.
[http://dx.doi.org/10.1016/j.amjcard.2010.03.032] [PMID: 20643246]
[29]
Codreanu I, Pegg TJ, Selvanayagam JB, et al. Details of left ventricular remodeling and the mechanism of paradoxical ventricular septal motion after coronary artery bypass graft surgery. J Invasive Cardiol 2011; 23(7): 276-82.
[PMID: 21725122]
[30]
Siddiqui MM, Jalal A, Sherwani M, Ahmad MZ. Right ventricular dysfunction after coronary artery bypass grafting is a reality of unknown cause and significance. Heart Surg Forum 2012; 15(4): E185-8.
[http://dx.doi.org/10.1532/HSF98.20111142] [PMID: 22917821]
[31]
Yadav H, Unsworth B, Fontana M, et al. Selective right ventricular impairment following coronary artery bypass graft surgery. Eur J Cardiothorac Surg 2010; 37(2): 393-8.
[http://dx.doi.org/10.1016/j.ejcts.2009.08.004] [PMID: 19758814]
[32]
Moya Mur JL, García Martín A, García Lledó A, et al. Geometrical and functional cardiac changes after cardiac surgery: A phisiopatological explanation based on speckle tracking. Int J Cardiovasc Imaging 2018; 34(12): 1905-15.
[http://dx.doi.org/10.1007/s10554-018-1424-z] [PMID: 30073630]
[33]
Raina A, Vaidya A, Gertz ZM, Susan Chambers , Forfia PR. Marked changes in right ventricular contractile pattern after cardiothoracic surgery: Implications for post-surgical assessment of right ventricular function. J Heart Lung Transplant 2013; 32(8): 777-83.
[http://dx.doi.org/10.1016/j.healun.2013.05.004] [PMID: 23773508]
[34]
Rösner A, Avenarius D, Malm S, et al. Changes in right ventricular shape and deformation following coronary artery bypass surgery-insights from echocardiography with strain rate and magnetic resonance imaging. Echocardiography 2015; 32(12): 1809-20.
[http://dx.doi.org/10.1111/echo.12973] [PMID: 26010320]
[35]
Fransen EJ, Maessen JG, Hermens WT, Glatz JF. Demonstration of ischemia-reperfusion injury separate from postoperative infarction in coronary artery bypass graft patients. Ann Thorac Surg 1998; 65(1): 48-53.
[http://dx.doi.org/10.1016/S0003-4975(97)01036-9] [PMID: 9456094]
[36]
Kovács A, Lakatos B, Tokodi M, Merkely B. Right ventricular mechanical pattern in health and disease: beyond longitudinal shortening. Heart Fail Rev 2019; 24(4): 511-20.
[http://dx.doi.org/10.1007/s10741-019-09778-1] [PMID: 30852772]
[37]
Brown SB, Raina A, Katz D, Szerlip M, Wiegers SE, Forfia PR. Longitudinal shortening accounts for the majority of right ventricular contraction and improves after pulmonary vasodilator therapy in normal subjects and patients with pulmonary arterial hypertension. Chest 2011; 140(1): 27-33.
[http://dx.doi.org/10.1378/chest.10-1136] [PMID: 21106653]
[38]
Haber I, Metaxas DN, Geva T, Axel L. Three-dimensional systolic kinematics of the right ventricle. Am J Physiol Heart Circ Physiol 2005; 289(5): H1826-33.
[http://dx.doi.org/10.1152/ajpheart.00442.2005] [PMID: 15964922]
[39]
Kaul S, Tei C, Hopkins JM, Shah PM. Assessment of right ventricular function using two-dimensional echocardiography. Am Heart J 1984; 107(3): 526-31.
[http://dx.doi.org/10.1016/0002-8703(84)90095-4] [PMID: 6695697]
[40]
Meluzín J, Spinarová L, Bakala J, et al. Pulsed doppler tissue imaging of the velocity of tricuspid annular systolic motion; a new, rapid, and non-invasive method of evaluating right ventricular systolic function. Eur Heart J 2001; 22(4): 340-8.
[http://dx.doi.org/10.1053/euhj.2000.2296] [PMID: 11161953]
[41]
Saxena N, Rajagopalan N, Edelman K, López-Candales A. Tricuspid annular systolic velocity: A useful measurement in determining right ventricular systolic function regardless of pulmonary artery pressures. Echocardiography 2006; 23(9): 750-5.
[http://dx.doi.org/10.1111/j.1540-8175.2006.00305.x] [PMID: 16999693]
[42]
David JS, Tousignant CP, Bowry R. Tricuspid annular velocity in patients undergoing cardiac operation using transesophageal echocardiography. J Am Soc Echocardiogr 2006; 19(3): 329-34.
[http://dx.doi.org/10.1016/j.echo.2005.09.013] [PMID: 16500497]
[43]
Alam M, Hedman A, Nordlander R, Samad B. Right ventricular function before and after an uncomplicated coronary artery bypass graft as assessed by pulsed wave Doppler tissue imaging of the tricuspid annulus. Am Heart J 2003; 146(3): 520-6.
[http://dx.doi.org/10.1016/S0002-8703(03)00313-2] [PMID: 12947373]
[44]
Bitcon CJ, Tousignant C. The effect of pericardial incision on right ventricular systolic function: A prospective observational study. Can J Anaesth 2017; 64(12): 1194-201.
[http://dx.doi.org/10.1007/s12630-017-0972-3] [PMID: 28983853]
[45]
Singh A, Huang X, Dai L, et al. Right ventricular function is reduced during cardiac surgery independent of procedural characteristics, reoperative status, or pericardiotomy. J Thorac Cardiovasc Surg 2020; 159(4): 1430-1438.e4.
[http://dx.doi.org/10.1016/j.jtcvs.2019.04.035] [PMID: 31133354]
[46]
Rong LQ, Yum B, Abouzeid C, et al. Echocardiographic predictors of intraoperative right ventricular dysfunction: A 2D and speckle tracking echocardiography study. Cardiovasc Ultrasound 2019; 17(1): 11.
[http://dx.doi.org/10.1186/s12947-019-0161-3] [PMID: 31174537]
[47]
Tamborini G, Muratori M, Brusoni D, et al. Is right ventricular systolic function reduced after cardiac surgery? A two- and three-dimensional echocardiographic study. Eur J Echocardiogr 2009; 10(5): 630-4.
[http://dx.doi.org/10.1093/ejechocard/jep015] [PMID: 19252190]
[48]
Keyl C, Schneider J, Beyersdorf F, et al. Right ventricular function after aortic valve replacement: A pilot study comparing surgical and transcatheter procedures using 3D echocardiography. Eur J Cardiothorac Surg 2016; 49(3): 966-71.
[http://dx.doi.org/10.1093/ejcts/ezv227] [PMID: 26130077]
[49]
Maffessanti F, Gripari P, Tamborini G, et al. Evaluation of right ventricular systolic function after mitral valve repair: A two-dimensional Doppler, speckle-tracking, and three-dimensional echocardiographic study. J Am Soc Echocardiogr 2012; 25(7): 701-8.
[http://dx.doi.org/10.1016/j.echo.2012.03.017] [PMID: 22542273]
[50]
Grønlykke L, Korshin A, Holmgaard F, et al. Marked reduction in right ventricular longitudinal contraction after cardiopulmonary bypass in patients with preserved right ventricular output. J Cardiothorac Vasc Anesth 2019; 33: S117-9.
[http://dx.doi.org/10.1053/j.jvca.2019.07.071]
[51]
Abdelmoneum MS, Elmeligy , Eldarky EA, Mohamad MM. Evaluation of the effects of coronary bypass grafting on the right ventricular function using speckle tracking echocardiography. J Cardiol Cardiovasc Med 2019; 4: 236-41.
[http://dx.doi.org/10.29328/journal.jccm.1001075]
[52]
Donauer M, Schneider J, Jander N, Beyersdorf F, Keyl C. Perioperative changes of right ventricular function in cardiac surgical patients assessed by myocardial deformation analysis and 3-dimensional echocardiography. J Cardiothorac Vasc Anesth 2020; 34(3): 708-18.
[http://dx.doi.org/10.1053/j.jvca.2019.08.026] [PMID: 31540753]
[53]
Korshin A, Grønlykke L, Holmgaard F, et al. Right ventricular transverse displacement increases following cardiac surgery: Possibly compensating loss in tricuspid annular plane systolic excursion (TAPSE). J Clin Monit Comput 2020; 34(6): 1139-48.
[http://dx.doi.org/10.1007/s10877-020-00466-2] [PMID: 31983013]
[54]
Salvo GD, Pergola V, Fadel B, Bulbul ZA, Caso P. Strain echocardiography and myocardial mechanics: from basics to clinical applications. J Cardiovasc Echogr 2015; 25(1): 1-8.
[http://dx.doi.org/10.4103/2211-4122.158415] [PMID: 28465921]
[55]
Toyoda T, Akasaka T, Watanabe N, et al. Evaluation of abnormal motion of interventricular septum after coronary artery bypass grafting operation: Assessment by ultrasonic strain rate imaging. J Am Soc Echocardiogr 2004; 17(7): 711-6.
[http://dx.doi.org/10.1016/j.echo.2004.03.033] [PMID: 15220894]
[56]
Zanobini M, Loardi C, Poggio P, et al. The impact of pericardial approach and myocardial protection onto postoperative right ventricle function reduction. J Cardiothorac Surg 2018; 13(1): 55.
[http://dx.doi.org/10.1186/s13019-018-0726-5] [PMID: 29866151]
[57]
Bhaya M, Sudhakar S, Sadat K, et al. Effects of antegrade versus integrated blood cardioplegia on left ventricular function evaluated by echocardiographic real-time 3-dimensional speckle tracking. J Thorac Cardiovasc Surg 2015; 149(3): 877-84.e1-5.
[58]
Becker M, Robbers L, Brouwer WP, et al. A cardiovascular magnetic resonance study on the short and long-term effects of coronary artery bypass graft surgery on the right systolic function. Madridge J Cardiol 2017; 2(1): 14-20.
[http://dx.doi.org/10.18689/mjc-1000105]
[59]
Unsworth B, Casula RP, Yadav H, et al. Contrasting effect of different cardiothoracic operations on echocardiographic right ventricular long axis velocities, and implications for interpretation of post-operative values. Int J Cardiol 2013; 165(1): 151-60.
[http://dx.doi.org/10.1016/j.ijcard.2011.08.031] [PMID: 21917325]
[60]
Dalén M, Oliveira Da Silva C, Sartipy U, et al. Comparison of right ventricular function after ministernotomy and full sternotomy aortic valve replacement: A randomized study. Interact Cardiovasc Thorac Surg 2018; 26(5): 790-7.
[http://dx.doi.org/10.1093/icvts/ivx422] [PMID: 29325064]
[61]
Lindqvist P, Holmgren A, Zhao Y, Henein MY. Effect of pericardial repair after aortic valve replacement on septal and right ventricular function. Int J Cardiol 2012; 155(3): 388-93.
[http://dx.doi.org/10.1016/j.ijcard.2010.10.049] [PMID: 21112100]
[62]
Michaux I, Filipovic M, Skarvan K, et al. A randomized comparison of right ventricular function after on-pump versus off-pump coronary artery bypass graft surgery. J Thorac Cardiovasc Surg 2011; 141(2): 361-7.
[http://dx.doi.org/10.1016/j.jtcvs.2010.02.023] [PMID: 20381082]
[63]
Khani M, Hosseintash M, Foroughi M, Naderian M, Khaheshi I. Assessment of the effect of off-pump coronary artery bypass (OPCAB) surgery on right ventricle function using strain and strain rate imaging. Cardiovasc Diagn Ther 2016; 6(2): 138-43.
[http://dx.doi.org/10.21037/cdt.2016.02.03] [PMID: 27054103]
[64]
Pegg TJ, Selvanayagam JB, Karamitsos TD, et al. Effects of off-pump versus on-pump coronary artery bypass grafting on early and late right ventricular function. Circulation 2008; 117(17): 2202-10.
[http://dx.doi.org/10.1161/CIRCULATIONAHA.107.735621] [PMID: 18413501]
[65]
Michaux I, Filipovic M, Skarvan K, et al. Effects of on-pump versus off-pump coronary artery bypass graft surgery on right ventricular function. J Thorac Cardiovasc Surg 2006; 131(6): 1281-8.
[http://dx.doi.org/10.1016/j.jtcvs.2006.01.035] [PMID: 16733158]
[66]
Goldstein JA, Tweddell JS, Barzilai B, Yagi Y, Jaffe AS, Cox JL. Importance of left ventricular function and systolic ventricular interaction to right ventricular performance during acute right heart ischemia. J Am Coll Cardiol 1992; 19(3): 704-11.
[http://dx.doi.org/10.1016/S0735-1097(10)80296-7] [PMID: 1538031]

© 2024 Bentham Science Publishers | Privacy Policy