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Current Forensic Science

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ISSN (Print): 2666-4844
ISSN (Online): 2666-4852

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Research Article

Genetic Analysis of Father-Daughter Incest Using Multifaceted STR Markers and Study of Inheritance Pattern of Alleles

Author(s): Hirak Ranjan Dash*, Ila Gautam, Anil Kumar Singh and Pankaj Shrivastava

Volume 1, 2023

Published on: 09 August, 2021

Article ID: e020921195431 Pages: 7

DOI: 10.2174/2666484401666210809114452

Price: $65

Abstract

Background: Two cases involving father-daughter incest, a rare report in the Indian population, have been analyzed in the current study. STR markers on both autosomal and sex chromosomes were employed to expound the cases.

Objective: The objective of this study is to confirm the identity of the fetus as a product of father-- daughter incest and to study the inheritance pattern of alleles in such cases.

Methods: Autosomal, X, and Y chromosomal analyses were performed to confirm the identity of the fetus. Statistical analyses were carried out to strengthen the evidentiary value of the obtained results.

Results: In both cases, the aborted fetus was found to be the product of an incestuous father-daughter relationship. The probability of paternity as well as maternity was found to be >99.9999% in both cases. Analysis of other paternity and forensic parameters also substantiated the inclusion of the alleged individuals. Father-daughter incest had a tremendous effect on the genome as evidenced from the dramatical decrease in unrelated alleles between father/child [16.66% (Case 1), 20% (Case 2)] and mother/child [26.66% (Case 1), 21.66% (Case 2)]. Genetic evidence also suggested an increased biallelic match i.e., 26.66% (Case 1) and 33.33% (Case 2) between mother and fetus, which are at par/ above the normal siblings’ values i.e., 26.66%.

Conclusion: A significant increase in the percentage of homozygous alleles (53.33% in both cases) was observed in the product of father-daughter incest. Both daughters share the same X chromosome from the father, which also suggested the case to be of father-daughter incest. Similarly, the same Y-STR profile between the male fetus and alleged father confirmed the correct pattern of inheritance of the Y chromosome in this case.

Keywords: DNA Fingerprinting, Father-daughter incest, STRs, Paternity Index (PI), Power of Exclusion (PE), Combined Random Men Not Excluded (CRMNE).

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