Cancer Metastasis as Disrupted Developmental Phenotype

Title: Cancer Metastasis as Disrupted Developmental Phenotype

Volume: 9 Issue: 1

Author(s): Hideshi Ishii and Toshiyuki Saito

Affiliation:

Keywords: Cancer, metastasis, notch, Bmp, SHH

Abstract: Cancer metastasis is a complex processes, associated with the invasion to tissues with extensive degradation of the surrounding normal components, penetration into vessels, circulation, and then invasion to normal tissues in body. It would be not surprising that tumor cells usurp pathways critical to the developing embryo during metastasis. For the better understanding of tumor metastasis, this review will highlight the recent progress and significance of the signal transduction pathways, relevant to developmental biology.

Cite this article as:

Ishii Hideshi and Saito Toshiyuki, Cancer Metastasis as Disrupted Developmental Phenotype, Current Genomics 2008; 9 (1) . https://dx.doi.org/10.2174/138920208783884919