Medicinal and Biological Significance of Phenoxazine Derivatives

Title:Medicinal and Biological Significance of Phenoxazine Derivatives

Volume: 21 Issue: 12

Author(s): Shruti Shukla*, Jaya Dwivedi, Neetu Yaduvanshi and Sonika Jain

Affiliation:

• Department of Chemistry, Banasthali Vidyapith, Banasthali, Rajasthan 304022,India

Keywords: Phenoxazine derivatives, pharmacological activity, biological significance, anticancer, antitumor, reactivity, synthesis.

Abstract: Since 1887, phenoxazine derivatives have attracted the attention of chemists due to their versatile utility, industrially and pharmacologically. Literature is found abundant with various pharmacological activities of phenoxazine derivatives like antitumor, anticancer, antifungal, antibacterial, anti-inflammatory, anti-diabetic, anti-viral, anti-malarial, anti-depressant, analgesic and many other drug resistance reversal activities. This review covers a detailed overview of the pharmacological application of phenoxazine nucleus, its chemistry and reactivity, and also illustrating the incorporation of different groups at different positions enhancing its biological application, besides some synthetic procedures.

Cite this article as:

Shukla Shruti *, Dwivedi Jaya , Yaduvanshi Neetu and Jain Sonika , Medicinal and Biological Significance of Phenoxazine Derivatives, Mini-Reviews in Medicinal Chemistry 2021; 21 (12) . https://dx.doi.org/10.2174/1389557520666201214102151