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当代阿耳茨海默病研究

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Review Article

阿尔茨海默氏病中的电磁场：近期临床前和临床研究的文献综述

卷 17, 期 11, 2020

页: [1001 - 1012] 页: 12

弟呕挨: 10.2174/1567205017666201130085853

价格: $65

摘要

阿尔茨海默氏病（AD）是一种神经退行性疾病，其特征在于神经元的逐渐丧失导致认知和记忆力衰退。 AD的主要体征包括大脑中淀粉样β（Aβ）蛋白在细胞外的不规则积累以及神经元内部tau蛋白的过度磷酸化。 Aβ表达或聚集的变化被认为是散发性和早发性AD病理生理的关键因素，并与AD患者的认知能力下降相关。尽管进行了数十年的研究，但目前治疗AD的方法仅是对症治疗，对减慢或逆转疾病进程无效。令人鼓舞的是，最近的证据表明，暴露于电磁场（EMF）可以延迟AD的发展并改善记忆力。这篇综述文章讨论了在细胞和行为水平上研究EMF和AD之间联系的体外和体内研究发现，并强调了EMF作为治疗AD的创新方法的潜在益处。

关键词: 阿尔茨海默氏病，β淀粉样蛋白，电磁场，动物研究，人体研究，神经元。

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