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Review Article

综述：小檗碱治疗结肠炎

卷 21, 期 13, 2020

页: [1385 - 1393] 页: 9

弟呕挨: 10.2174/1389450121666200621193758

价格: $65

摘要

小檗碱(Brb)是一种著名的天然化合物，仅在小檗和其他小檗科植物中发现，如印度小檗、小檗和冬青叶小檗。这种植物衍生的天然化合物具有多种治疗作用，包括抗氧化、抗炎、抗糖尿病和抗肿瘤。多项研究表明小檗碱（Brb）具有很强的抗炎活性，能够降低促炎细胞因子的水平，同时提高抗炎细胞因子的浓度，使其适合于炎症性疾病的治疗。结肠炎是一种慢性炎症性肠病。许多因素参与了结肠炎的发展，炎症和氧化应激似乎是最重要的因素。就小檗碱（Brb）的抗炎和抗氧化作用而言，给药对治疗结肠炎似乎是有益的。本文就小檗碱（Brb）在结肠炎治疗中的保护作用及其对分子通路的影响进行了讨论。

关键词: 抗氧化，抗炎，小檗碱，结肠炎，炎症性肠病，冬青叶小檗

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