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Current Medicinal Chemistry

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ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Donepezil Hydrochloride (E2020) and Other Acetylcholinesterase Inhibitors

Author(s): Hachiro Sugimoto, Yoshiharu Yamanish, Youichi Iimura and Yoshiyuki Kawakami

Volume 7, Issue 3, 2000

Page: [303 - 339] Pages: 37

DOI: 10.2174/0929867003375191

Price: $65

Abstract

A wide range of evidence shows that acetylcholinesterase (AChE) inhibitors can

Keywords: donepezil hydrochloride, acetylcholinesterase inhibitors, alzheimer s disease, AChE inhibitors, cortical cholinergic neurotransmission, hepatotxic liability, physostigmine, cholineric enhancement therapy, ACh releasers, M1 M3 Receptor agonists, nicotinic agonists, velnacrine, amiridine, eptastigmine, galanthamine, rivastigmine, metrifonate, huperzine A, donepezil hydrocloride, anti AChE Activity, n alkyl analogs, molecular modeling, receptor dependent docking, crystal structure, BuChE, Brain acetylcholine concentrations, TAK 147, anti inflammatory agents, alzheimer s disease treatment, estrogen replacement therapy, anti oxidants, anti amyloid, galanin receptor antagonist

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