Abstract
Autoimmune thyroid diseases are the most common autoimmune endocrine disorders. Expression of thyroid dysfunction is dependent upon the interaction of genetic factors and environmental exposures. The genes identified so far account for only a small portion of genetic susceptibility for autoimmune thyroid disease. A number of environmental exposures are associated with exposing thyroid dysfunction in subjects with autoimmune thyroid disease and some are clearly identified as inducing thyroid autoimmunity although this is actually less common. Understanding the relationship between environment and the genetic background should help in identifying patients at risk and may provide therapeutic options for the future.
Keywords: Graves’ disease, hashimoto’s thyroiditis, thyroid autoimmunity.
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