Abstract
• The most important technical tools that have improved speed and safety of liver resection are: staplers, sealers, and ablation devices.
• Staplers now allow reliable and rapid closure of major blood vessels.
• Sealers allow secure transection of liver parenchyma, minimizing bleeding and securing small bile ducts.
• Ablation instruments allow a parenchymal sparing alternative to resection for deep, small tumors, and can be combined with simultaneous major liver resection to extend possibility of curative therapy.