Comprehensive Practical Hepatology

Sytemic Abnormalities in Liver Disease

Author(s): Yukihiro Shimizu and Masami Minemura

Pp: 157-164 (8)

DOI: 10.2174/9781681082059116010010

* (Excluding Mailing and Handling)

Abstract

Systemic abnormalities are often seen in patients with liver diseases. Especially, cardiopulmonary or renal diseases complicated by advanced liver disease are sometimes serious and may determine the quality of life and prognosis of patients. Therefore, both hepatologists and non-hepatologists should pay attention to these abnormalities in the management of patients with liver diseases.


Keywords: Cardiomyopathy, coronary heart disease, diabetes mellitus, liver injury, pulmonary disease, renal disease, thyroid disease.

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      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
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      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
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      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
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      • 16. app/Models/Subject.php:238
      • 17. app/Http/Controllers/ChapterController.php:1434
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
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      820μsalphaeurekaselec_live_10_06_2022Subject.php#238
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      • 14. app/Models/Subject.php:238
      • 15. app/Http/Controllers/ChapterController.php:1434
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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      470μsalphaeurekaselec_live_10_06_2022Subject.php#255
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      • 16. app/Models/Subject.php:255
      • 17. app/Http/Controllers/ChapterController.php:1435
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      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
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      500μsalphaeurekaselec_live_10_06_2022Subject.php#255
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      • 14. app/Models/Subject.php:255
      • 15. app/Http/Controllers/ChapterController.php:1435
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
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      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
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      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
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      370μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
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      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1465
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
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      310μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
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      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1478
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
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      670μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
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      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1518
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 309813860 and j.to_ip >=309813860 )) and ((j.from_date <= 1740775672 and j.to_date >= 1740775672 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 8237) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 309813860 and j.to_ip >=309813860 )) and ((j.from_date <= 1740775672 and j.to_date >= 1740775672 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 8237) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 309813860 and j.to_ip >=309813860 )) and ((j.from_date <= 1740775672 and j.to_date >= 1740775672 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 8237)
      710μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1549
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 1887 and `b`.`banner_from_date` <= 1740775672 and `b`.`banner_to_date` >= 1740775672 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.17msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 1887
      • 3: 1740775672
      • 4: 1740775672
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='4f3dfecbd429861e32e0b2c941ab4705'
      280μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:291
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Keywords
    7Keywords.php#?
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        rljasfrutBmgCmQedZKGSPm1EMWA3RQ9a7LxWH8w
        uc_cart_id
        4f3dfecbd429861e32e0b2c941ab4705
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/8237" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/8237
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:16 [ "x-https" => array:1 [ 0 => "1" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] "priority" => array:1 [ 0 => "u=0, i" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate, br, zstd" ] "sec-fetch-dest" => array:1 [ 0 => "document" ] "sec-fetch-user" => array:1 [ 0 => "?1" ] "sec-fetch-mode" => array:1 [ 0 => "navigate" ] "sec-fetch-site" => array:1 [ 0 => "none" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "sec-ch-ua-platform" => array:1 [ 0 => ""Windows"" ] "sec-ch-ua-mobile" => array:1 [ 0 => "?0" ] "sec-ch-ua" => array:1 [ 0 => ""HeadlessChrome";v="129", "Not=A?Brand";v="8", "Chromium";v="129"" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] ]
        request_cookies
        []
        
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Fri, 28 Feb 2025 20:47:52 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IjY3eUJvZmEvZWwrUXhjeE9yOUEvOGc9PSIsInZhbHVlIjoid0VYeEN0anVGbVFpaWtGVHloN0pQd1dVVWZKc1AyN0NXWTE1eTNNREV5OVpOd1BVSjBic3NiUnlNN2xlYW5tNTU4WnZaNjRGWWV6UnVtQ3RzM1hnazdzRWNuN3Q1U1pCZjV0ekdhZGY3cnc2bWU2TDdaN3p4b0N1OVlrVE03V3ciLCJtYWMiOiJkMmMyNDg2YTlmOTVhYTkxZGQyOWU5ZTI3NTRhZmFlMjk2MjEwYTZmNDk4NmFiNzZhOTkzOTAwM2E5M2VlNTFlIiwidGFnIjoiIn0%3D; expires=Mon, 03 Mar 2025 08:47:52 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6IjY3eUJvZmEvZWwrUXhjeE9yOUEvOGc9PSIsInZhbHVlIjoid0VYeEN0anVGbVFpaWtGVHloN0pQd1dVVWZKc1AyN0NXWTE1eTNNREV5OVpOd1BVSjBic3NiUnlNN2xlYW5tNTU4WnZaN" 1 => "alphaeurekaselectnet_session=eyJpdiI6Ik9Jbm9rRXFEK1VoQzdjMzdndWRHU0E9PSIsInZhbHVlIjoiOWNQVmRjRXdqUmErRW9QcUlXdnJDWnFOaVRML2tFcXU0RDhQdW8ySU1UYmR2dFlCekIxME1sek5WTGJuMDVzRmlld0FxajY0U3FWOEpVQ1AxU05nQ0VaUHNjdFAvMVdFbzI4S3B2VXZNYmU3aTN4Vk9qWEtCd21yY0RYd3BjMGYiLCJtYWMiOiI5NTY0MjI3YzZlMmQ0MGExOWEzMWY4Nzk0ZWFlZThmZDMwOGMyZjlhODVlNWMyNzdhNzlkMjA2ODBiOTUwMWM4IiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6Ik9Jbm9rRXFEK1VoQzdjMzdndWRHU0E9PSIsInZhbHVlIjoiOWNQVmRjRXdqUmErRW9QcUlXdnJDWnFOaVRML2tFcXU0RDhQdW8ySU1UYmR2dFlCekIxME1sek5" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IjY3eUJvZmEvZWwrUXhjeE9yOUEvOGc9PSIsInZhbHVlIjoid0VYeEN0anVGbVFpaWtGVHloN0pQd1dVVWZKc1AyN0NXWTE1eTNNREV5OVpOd1BVSjBic3NiUnlNN2xlYW5tNTU4WnZaNjRGWWV6UnVtQ3RzM1hnazdzRWNuN3Q1U1pCZjV0ekdhZGY3cnc2bWU2TDdaN3p4b0N1OVlrVE03V3ciLCJtYWMiOiJkMmMyNDg2YTlmOTVhYTkxZGQyOWU5ZTI3NTRhZmFlMjk2MjEwYTZmNDk4NmFiNzZhOTkzOTAwM2E5M2VlNTFlIiwidGFnIjoiIn0%3D; expires=Mon, 03-Mar-2025 08:47:52 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6IjY3eUJvZmEvZWwrUXhjeE9yOUEvOGc9PSIsInZhbHVlIjoid0VYeEN0anVGbVFpaWtGVHloN0pQd1dVVWZKc1AyN0NXWTE1eTNNREV5OVpOd1BVSjBic3NiUnlNN2xlYW5tNTU4WnZaN" 1 => "alphaeurekaselectnet_session=eyJpdiI6Ik9Jbm9rRXFEK1VoQzdjMzdndWRHU0E9PSIsInZhbHVlIjoiOWNQVmRjRXdqUmErRW9QcUlXdnJDWnFOaVRML2tFcXU0RDhQdW8ySU1UYmR2dFlCekIxME1sek5WTGJuMDVzRmlld0FxajY0U3FWOEpVQ1AxU05nQ0VaUHNjdFAvMVdFbzI4S3B2VXZNYmU3aTN4Vk9qWEtCd21yY0RYd3BjMGYiLCJtYWMiOiI5NTY0MjI3YzZlMmQ0MGExOWEzMWY4Nzk0ZWFlZThmZDMwOGMyZjlhODVlNWMyNzdhNzlkMjA2ODBiOTUwMWM4IiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6Ik9Jbm9rRXFEK1VoQzdjMzdndWRHU0E9PSIsInZhbHVlIjoiOWNQVmRjRXdqUmErRW9QcUlXdnJDWnFOaVRML2tFcXU0RDhQdW8ySU1UYmR2dFlCekIxME1sek5" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "rljasfrutBmgCmQedZKGSPm1EMWA3RQ9a7LxWH8w" "uc_cart_id" => "4f3dfecbd429861e32e0b2c941ab4705" "_previous" => array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/8237" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-28 20:47:52GET/chapter/8237112199