Frontiers in Clinical Drug Research-Anti Infectives

Volume: 1

Plant Derived Edible Vaccines and Therapeutics

Author(s): Emrah Altindis, Sultan Gulce Iz, Mehmet Ozgun Ozen, Pinar Nartop, Ismet Deliloglu Gurhan and Aynur Gurel

Pp: 200-236 (37)

DOI: 10.2174/9781608058549114010007

* (Excluding Mailing and Handling)

Abstract

Defining the molecular basis of the infectious diseases by the highly accumulated data on genetics and molecular biology facilitated developing new prophylactic and therapeutic vaccination strategies against human and animal diseases. On the other hand, vaccine development process still has many technical and economical limitations. Therefore, low-income countries, which do not have powerful healthcare infrastructure, neither produce their own vaccines nor benefit enough from the current vaccination programs. In this aspect, plants are promising to be used as biofactories for producing edible vaccines and several therapeutics due to their easy manipulations and also low-cost manufacturing properties. In this chapter, the advantages, limitations of the edible vaccines, the studies related to plant-derived edible vaccines and therapeutics up to date are summarized.


Keywords: Plant derived edible vaccines, therapeutics, recombinant proteins.

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      • 13. app/Models/UserAccess/UserAccess.php:1266
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      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316548017 and j.to_ip >=316548017 )) and ((j.from_date <= 1739847475 and j.to_date >= 1739847475 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 6436) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316548017 and j.to_ip >=316548017 )) and ((j.from_date <= 1739847475 and j.to_date >= 1739847475 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 6436) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316548017 and j.to_ip >=316548017 )) and ((j.from_date <= 1739847475 and j.to_date >= 1739847475 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 6436)
      920μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1549
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 1507 and `b`.`banner_from_date` <= 1739847475 and `b`.`banner_to_date` >= 1739847475 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.46msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 1507
      • 3: 1739847475
      • 4: 1739847475
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='399c1b9c82b552fade0c29fb4393a936'
      290μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Keywords
    3Keywords.php#?
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        pDpsOpvuANaByRnrtB7xB6BGYbj1e2CeCBWPd7LF
        uc_cart_id
        399c1b9c82b552fade0c29fb4393a936
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/6436" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/6436
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
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        request_cookies
        0 of 0
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        response_headers
        0 of 0
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        array:5 [ "_token" => "pDpsOpvuANaByRnrtB7xB6BGYbj1e2CeCBWPd7LF" "uc_cart_id" => "399c1b9c82b552fade0c29fb4393a936" "_previous" => array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/6436" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-18 02:57:55GET/chapter/6436112195