Abstract
Several experts in the various fields of SMGT have contributed valuable knowledge to this eBook. This chapter offers a synthesis of the key concepts covered throughout the book, and critically evaluates the current status and controversial aspects of SMGT.
Keywords: Augmented uptake, Autouptake, En masse GM, Episomal transgene, Gene targeting, Germline modification, Horizontal inheritance, Human artificial chromosome, SMGT scepticism, Zinc-finger nuclease.