Functional Molecular Imaging In Hepatology

Cholangiocarcinoma

Author(s): Hanne Prytz

Pp: 95-103 (9)

DOI: 10.2174/978160805290511201010095

Abstract

Cholangiocarcinoma (CC) is the second most common primary hepatic malignancy. Primary sclerosing cholangitis (PSC) predisposes for CC with a yearly incidence of 1.5%. Symptoms of CC are late and therefore the prognosis is poor. Ultrasonography (US), computer tomography (CT), magnetic resonance imaging (MRI), and cholangiographic techniques with cytology are the best imaging modalities, but these techniques are less useful for detection of tumour recurrence after surgery and metastases. Positron emission tomography (PET) using [18F]fluoro-2-deoxy-D-glucose (18F-FDG PET) has a diagnostic sensitivity for diagnosis of the primary tumour in CC complicating PSC ranging from 0-1.0 and a specificity of 0.67-1.0 in small studies of advanced PSC. The sensitivity and specificity of 18F-FDG PET for diagnosis of CC in patients with suspected bile duct cancer were 0.61-0.94 and 0.80- 1.0, respectively. With 18F-FDG PET/CT, sensitivity and specificity were 0.68-1.0 and 0.63-1.0, respectively, in this group of patients. Mass lesions and intrahepatic CC were more readily diagnosed than tumours with an infiltrating growth pattern and extrahepatic CC. Direct comparison of 18F-FDG PET, 18F-FDG PET/CT on 1 hand and CT on the other for diagnosis of the primary tumour showed no significant differences in sensitivity or specificity between the modalities. This also holds true for detection of regional lymph node metastases. However, 18F-FDG PET and 18F-FDG PET/CT performed better than CT for diagnosis of both recurrence of CC and distant metastases. The usefulness of 18FFDG PET/CT for screening and surveillance of PSC-patients for CC remains to be established.


Keywords: Primary sclerosing cholangitis; Liver transplantation; Liver PET/CT.

Related Journals
Related Books
© 2025 Bentham Science Publishers | Privacy Policy
Request history8.2.27PHP Version429msRequest Duration26MBMemory UsageGET chapter/{id}/{param?}Route
  • warninglog[20:43:55] LOG.warning: Optional parameter $id declared before required parameter $request is implic...
  • Booting (180ms)time
  • Application (249ms)time
  • 1 x Application (58.1%)
    249ms
    1 x Booting (41.9%)
    180ms
    12 templates were rendered
    • ebook.chapter_detailschapter_details.blade.php#?blade
    • layouts.chapter_header_sectionchapter_header_section.blade.php#?blade
    • ebook.chapter_top_bannerchapter_top_banner.blade.php#?blade
    • ebook.chapter_bottom_bannerchapter_bottom_banner.blade.php#?blade
    • ebook.ebook_right_bannerebook_right_banner.blade.php#?blade
    • includes.inc_related_journalsinc_related_journals.blade.php#?blade
    • includes.inc_related_ebooksinc_related_ebooks.blade.php#?blade
    • layouts.appapp.blade.php#?blade
    • layouts._login_access_login_access.blade.php#?blade
    • layouts._header_header.blade.php#?blade
    • layouts._main_menu_main_menu.blade.php#?blade
    • layouts._footer_menu_footer_menu.blade.php#?blade
    uri
    GET chapter/{id}/{param?}
    middleware
    web, check_user_access
    controller
    App\Http\Controllers\ChapterController@GetChapterDetails
    namespace
    App\Http\Controllers
    where
    as
    chapter
    file
    app/Http/Controllers/ChapterController.php:1350-1704
    17 statements were executed99.4ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('316574772','',1,1740775435,1740775435) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1740775435
      10.65msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('316574772','/chapter/3613',1,1740775435,1740775435)
      20.19msalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 316574772 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316574772) limit 1
      24.03msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 316574772
      • 1: 316574772
      • 2: 316574772
      • 3: 316574772
      • 4: 316574772
      • 5: 316574772
      • 6: 316574772
      • 7: 316574772
      • 8: 316574772
      • 9: 316574772
      • 10: 316574772
      • 11: 316574772
      • 12: 316574772
      • 13: 316574772
      • 14: 316574772
      • 15: 316574772
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • select * from `chapter` where `chapter_id` = '3613' limit 1
      350μsalphaeurekaselec_live_10_06_2022ChapterController.php#1406
      Bindings
      • 0: 3613
      Backtrace
      • 16. app/Http/Controllers/ChapterController.php:1406
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`chapter_id` = '3613' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      2.02msalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 3613
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ChapterController.php:1411
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `keywords` where `chapter_id` = '3613'
      30.27msalphaeurekaselec_live_10_06_2022ChapterController.php#1415
      Bindings
      • 0: 3613
      Backtrace
      • 15. app/Http/Controllers/ChapterController.php:1415
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select * from `ebook` where `ebook_id` = 233 limit 1
      480μsalphaeurekaselec_live_10_06_2022ChapterController.php#1430
      Bindings
      • 0: 233
      Backtrace
      • 16. app/Http/Controllers/ChapterController.php:1430
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select count(*) as aggregate from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `e`.`ebook_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=233) and se.ebook_id!=233 and v.ebook_status='1'
      3.64msalphaeurekaselec_live_10_06_2022Subject.php#238
      Backtrace
      • 16. app/Models/Subject.php:238
      • 17. app/Http/Controllers/ChapterController.php:1434
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select distinct v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `e`.`ebook_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=233) and se.ebook_id!=233 and v.ebook_status='1' limit 10 offset 0
      1.13msalphaeurekaselec_live_10_06_2022Subject.php#238
      Backtrace
      • 14. app/Models/Subject.php:238
      • 15. app/Http/Controllers/ChapterController.php:1434
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as aggregate from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=233)
      610μsalphaeurekaselec_live_10_06_2022Subject.php#255
      Backtrace
      • 16. app/Models/Subject.php:255
      • 17. app/Http/Controllers/ChapterController.php:1435
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select distinct j.nid as journal_nid,j.title,j.subtitle,j.issn,j.eissn,j.keyword,sj.journal_id,j.image_file_name,j.flyer_link from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=233) limit 10 offset 0
      670μsalphaeurekaselec_live_10_06_2022Subject.php#255
      Backtrace
      • 14. app/Models/Subject.php:255
      • 15. app/Http/Controllers/ChapterController.php:1435
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `e`.*, `a`.*, `y`.`year`, `e`.`ebook_volume_id` as `ebook_volume_id`, `a`.`ebook_volume_id` as `ebk_vol_id`, `e`.`ebook_id` as `ebk_ebook_id` from `ebook_volume` as `e` left join `author` as `a` on `e`.`ebook_volume_id` = `a`.`ebook_volume_id` left join `year` as `y` on `y`.`id` = `e`.`year_id` where `e`.`ebook_volume_id` = 1050 and `e`.`is_uploaded` = 1
      2.3msalphaeurekaselec_live_10_06_2022EbookVolume.php#271
      Bindings
      • 0: 1050
      • 1: 1
      Backtrace
      • 13. app/Models/EbookVolume.php:271
      • 14. app/Http/Controllers/ChapterController.php:1438
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) rcd from `ebook_volume` where `ebook_id` = 233 and ebook_volume_id <> 1050 limit 1
      380μsalphaeurekaselec_live_10_06_2022EbookVolume.php#999
      Bindings
      • 0: 233
      Backtrace
      • 14. app/Models/EbookVolume.php:999
      • 15. app/Http/Controllers/ChapterController.php:1462
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from ebook_access where content_type_id = '3613' and content_type = 'c' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      420μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1465
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from ebook_access where content_type_id = '1050' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      420μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1478
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 1050 and `b`.`banner_from_date` <= 1740775435 and `b`.`banner_to_date` >= 1740775435 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.55msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 1050
      • 3: 1740775435
      • 4: 1740775435
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='fd75c65d48bf92b8eb5202098d6b810d'
      290μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:291
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Keywords
    1Keywords.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        FxyU4iMpCMiYcRkQ5zEwy4SvM2Bdzoh9Re2PMcuH
        uc_cart_id
        fd75c65d48bf92b8eb5202098d6b810d
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/3613" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/3613
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:17 [ "x-https" => array:1 [ 0 => "1" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] "priority" => array:1 [ 0 => "u=0, i" ] "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6IjVXYmF1Yy9iYnl1Y200TXMwR2V1NFE9PSIsInZhbHVlIjoiaDRSb2UvdHJJUVd2T2VDQThWM3dYZ012QUVYemRHclA2ejg2QTBibm1Rcz0iLCJtYWMiOiI3MDFhZWFkN2M3YzAyYzRhNWJjNTBmNThiNjdkNTI2YjgzMjQzM2IzM2VmNmU2YWM0ZjFmOTFhOWQ5ZmYzYzc5IiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6IjVXYmF1Yy9iYnl1Y200TXMwR2V1NFE9PSIsInZhbHVlIjoiaDRSb2UvdHJJUVd2T2VDQThWM3dYZ012QUVYemRHclA2ejg2QTBibm1Rcz0iLCJtYWMiOiI3MDFhZWFkN2M3YzAy" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate, br, zstd" ] "sec-fetch-dest" => array:1 [ 0 => "document" ] "sec-fetch-user" => array:1 [ 0 => "?1" ] "sec-fetch-mode" => array:1 [ 0 => "navigate" ] "sec-fetch-site" => array:1 [ 0 => "none" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "sec-ch-ua-platform" => array:1 [ 0 => ""Windows"" ] "sec-ch-ua-mobile" => array:1 [ 0 => "?0" ] "sec-ch-ua" => array:1 [ 0 => ""HeadlessChrome";v="129", "Not=A?Brand";v="8", "Chromium";v="129"" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Fri, 28 Feb 2025 20:43:55 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6Im9uWnVsSForMWJoSjVqaVZhanR6eEE9PSIsInZhbHVlIjoiOVJROHV5VG5pS09ldUI2eS9zaThtNm1OSzh6TVNxSjdWU3QvTEt5QjJIMFl4YzVOU3dPMS9ySDN3VlQwTWpGL2h1MWt3bndJcDE3YW9IZDNQL1FWM0c3YTEyRHcvYlNQWUUzNGdEZ0tJQWpHa2ZuTEpJU2ZodFdqY015cDdoMFQiLCJtYWMiOiIyZDBiMDcxMmViN2FmYmM0ODRkZjc0MWFiZTI0NDYyNjNkNTIwYmZkYzQ5YWJkMzA4MGE2YzQ5Nzg5ODQ5OTFjIiwidGFnIjoiIn0%3D; expires=Mon, 03 Mar 2025 08:43:55 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6Im9uWnVsSForMWJoSjVqaVZhanR6eEE9PSIsInZhbHVlIjoiOVJROHV5VG5pS09ldUI2eS9zaThtNm1OSzh6TVNxSjdWU3QvTEt5QjJIMFl4YzVOU3dPMS9ySDN3VlQwTWpGL2h1MWt3b" 1 => "alphaeurekaselectnet_session=eyJpdiI6IkxwRi9Rc0hObzUvMDFYTFJzWXJTOFE9PSIsInZhbHVlIjoiNDREZVkza2svZ3dmRllHd0dkWkxuSlRiYWlVUG8zeXlvb2lEcWgxR2ZuQkFPR0ZOSkVrdjd5QXVRN1hvV0xxcXFyWk92WUJWeGVPL1QzUndjRmdXT2owZ09SS21ocDZxR3BTSUlyVGR6NGt3SjZiZjkzZ0x0emtmMjMyczBQK28iLCJtYWMiOiIzNjJmZjZmZDBlN2VmYjAyMWY0OWE1MzIyMDU5NmMxMGMzODI4YTMwYTg3YWU5YjZmYzI2MDdlNmQ3NDg4N2FhIiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6IkxwRi9Rc0hObzUvMDFYTFJzWXJTOFE9PSIsInZhbHVlIjoiNDREZVkza2svZ3dmRllHd0dkWkxuSlRiYWlVUG8zeXlvb2lEcWgxR2ZuQkFPR0ZOSkVrdjd5QXV" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6Im9uWnVsSForMWJoSjVqaVZhanR6eEE9PSIsInZhbHVlIjoiOVJROHV5VG5pS09ldUI2eS9zaThtNm1OSzh6TVNxSjdWU3QvTEt5QjJIMFl4YzVOU3dPMS9ySDN3VlQwTWpGL2h1MWt3bndJcDE3YW9IZDNQL1FWM0c3YTEyRHcvYlNQWUUzNGdEZ0tJQWpHa2ZuTEpJU2ZodFdqY015cDdoMFQiLCJtYWMiOiIyZDBiMDcxMmViN2FmYmM0ODRkZjc0MWFiZTI0NDYyNjNkNTIwYmZkYzQ5YWJkMzA4MGE2YzQ5Nzg5ODQ5OTFjIiwidGFnIjoiIn0%3D; expires=Mon, 03-Mar-2025 08:43:55 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6Im9uWnVsSForMWJoSjVqaVZhanR6eEE9PSIsInZhbHVlIjoiOVJROHV5VG5pS09ldUI2eS9zaThtNm1OSzh6TVNxSjdWU3QvTEt5QjJIMFl4YzVOU3dPMS9ySDN3VlQwTWpGL2h1MWt3b" 1 => "alphaeurekaselectnet_session=eyJpdiI6IkxwRi9Rc0hObzUvMDFYTFJzWXJTOFE9PSIsInZhbHVlIjoiNDREZVkza2svZ3dmRllHd0dkWkxuSlRiYWlVUG8zeXlvb2lEcWgxR2ZuQkFPR0ZOSkVrdjd5QXVRN1hvV0xxcXFyWk92WUJWeGVPL1QzUndjRmdXT2owZ09SS21ocDZxR3BTSUlyVGR6NGt3SjZiZjkzZ0x0emtmMjMyczBQK28iLCJtYWMiOiIzNjJmZjZmZDBlN2VmYjAyMWY0OWE1MzIyMDU5NmMxMGMzODI4YTMwYTg3YWU5YjZmYzI2MDdlNmQ3NDg4N2FhIiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6IkxwRi9Rc0hObzUvMDFYTFJzWXJTOFE9PSIsInZhbHVlIjoiNDREZVkza2svZ3dmRllHd0dkWkxuSlRiYWlVUG8zeXlvb2lEcWgxR2ZuQkFPR0ZOSkVrdjd5QXV" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "FxyU4iMpCMiYcRkQ5zEwy4SvM2Bdzoh9Re2PMcuH" "uc_cart_id" => "fd75c65d48bf92b8eb5202098d6b810d" "_previous" => array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/3613" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-28 20:43:55GET/chapter/3613112173