Abstract
Oxygen and Nitrogen containing five-membered heterocyclic compounds
have been the target of intense investigation in the last two decades to discover potent
biologically active compounds as anti-inflammatory agents. The related studies
comprising of fascinating oxazole-based derivatives include oxazoles, isoxazoles,
oxazolines, and oxadiazoles, as therapeutic agents, which have become an interesting
topic.Therefore, noticeable achievements have been accomplished in the field of antiinflammatory studies. This chapter will discuss some latest updates on the synthesis
and anti-inflammatory studies of these oxazole-based derivatives, which we hope will
be beneficial to synthetic organic and medicinal chemists.