Abstract
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) leads to
coronavirus disorder (COVID-19). It was detected in Wuhan City, China, in December
2019 and extended to different provinces in China. The drug discovery strategy that
holds the thrust of the COVID-19 pandemic is the existing trial of broad-spectrum
antiviral drugs. However, molecular docking combined with chemical synthesis assists
in discovering various synthetic agents, above one-third of FDA (Food and Drug
Administration)- are naturally occurring products as approved drugs. Natural derivative
products from different sources of fungus, plant and marine have been abundant in
nutrition/ phytochemicals to prevent various disease discoveries for many diseases’
prevention. There are scarcely any country that is left intact by the coronavirus
outbreak. Only the considerable well-known health threat still now requires it to be
managed as early as possible. To date, there is no development of drugs or vaccines
that have been proven clinically against COVID-19. Various secondary
phytoconstituents with antiviral activities have been extracted from medicinal herbs.
Different research works have been demonstrated all over the globe to find antiviral
medication effectiveness against SARS-CoV-2 in COVID-19 pandemic. The best
preventive measures against COVID-19 infections would be searching for the
molecules responsible for modifying or disturbing any pathways related to the virus
replication cycle. Natural compounds are capable of altering or inhibiting the
configuration of the structural protein of (spike glycoprotein), non-structural proteins
(3-chymotrypsin-like protease, papain-like protease, helicase, and RdRP) and accessory
proteins encoded by the SARS-CoV-2 genome that are required to be investigated.Hence, various natural products and herbal extracts may prove as potent therapeutics in
treating the symptoms related to SARS-CoV-2 infection. In this context, we will
present some traditional plants/herbs that are found effective against viral activities and
reduce the contamination risk by Coronavirus and cure some symptoms of COVID-19,
mainly respiratory problems.