Recent Advances in Biosensor Technology

Volume: 2

3D Bioprinting of Advanced Bioinks for Tissue Regeneration and Biosensor Development

Author(s): Alma Tamunonengiofori Banigo* and Chinedu Chamberlin Obasi

Pp: 38-71 (34)

DOI: 10.2174/9789815136418123020007

* (Excluding Mailing and Handling)

Abstract

Three-dimensional (3D) bioprinting technology has become a unique system for tissue regeneration and biosensor development by controlled deposition of bioinks to produce complex constructs. Different bioprinters including laser-assisted and extrusion-based have been introduced and used to produce constructs with high resolution, cell viability and shape fidelity for tissue development. In addition, microfluidic technology, organ-on-a-chip and electrospinning technology are used to produce biosensing products to diagnose and monitor living systems. One of the most critical materials used for bioprinting is bioink. Several bioinks of an advanced level and different compositions have been developed too. Here, we briefly highlighted the characteristics, advantages, and disadvantages of some bioprinters and advanced bioinks that have been developed recently. We also stated some tissue engineering applications with the use of 3D bioprinting. Lastly, we mentioned a few key areas for main focus in the future.

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      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1518
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314538714 and j.to_ip >=314538714 )) and ((j.from_date <= 1739959620 and j.to_date >= 1739959620 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 20268) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314538714 and j.to_ip >=314538714 )) and ((j.from_date <= 1739959620 and j.to_date >= 1739959620 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 20268) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 314538714 and j.to_ip >=314538714 )) and ((j.from_date <= 1739959620 and j.to_date >= 1739959620 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 20268)
      880μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1549
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 3575 and `b`.`banner_from_date` <= 1739959620 and `b`.`banner_to_date` >= 1739959620 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.55msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 3575
      • 3: 1739959620
      • 4: 1739959620
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='6eb5c5fff8bd405e39e21d6c0b08edff'
      330μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        QokpgNTeqvLARmGNqrNwC940fymV7ijDo2vMlrDv
        uc_cart_id
        6eb5c5fff8bd405e39e21d6c0b08edff
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/20268" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/20268
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:17 [ "x-https" => array:1 [ 0 => "1" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] "priority" => array:1 [ 0 => "u=0, i" ] "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6Ii9OYjZCOFVLWWF2bU1WRkpwTWNHRkE9PSIsInZhbHVlIjoicFZqVUdrSVJOQWhhSEZMaU9LUHcraXZvSFJBRmpUTEN1SVhnYUJuRmtwbz0iLCJtYWMiOiIzNjFmODE5YTNiZTNhZWUzNjI5M2NlZjllYmE1ZmEwNzAzNmE4ZDgyNjkxNGQ3MmNkZjExMTk2YmQ3MTVkYzVhIiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6Ii9OYjZCOFVLWWF2bU1WRkpwTWNHRkE9PSIsInZhbHVlIjoicFZqVUdrSVJOQWhhSEZMaU9LUHcraXZvSFJBRmpUTEN1SVhnYUJuRmtwbz0iLCJtYWMiOiIzNjFmODE5YTNiZTNh" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate, br, zstd" ] "sec-fetch-dest" => array:1 [ 0 => "document" ] "sec-fetch-user" => array:1 [ 0 => "?1" ] "sec-fetch-mode" => array:1 [ 0 => "navigate" ] "sec-fetch-site" => array:1 [ 0 => "none" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "sec-ch-ua-platform" => array:1 [ 0 => ""Windows"" ] "sec-ch-ua-mobile" => array:1 [ 0 => "?0" ] "sec-ch-ua" => array:1 [ 0 => ""HeadlessChrome";v="129", "Not=A?Brand";v="8", "Chromium";v="129"" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Wed, 19 Feb 2025 10:07:00 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IkF6eXRzVVpudkNpSnBjNzEzOTFvdmc9PSIsInZhbHVlIjoiSWxIWS92MjJRRGhhd1ZaYUh0NHEzYmJnZXRxc3M0UmJ5dGlJQ1ROSlNLZjJuZUxRQVkyM1I3QVJRdUVJNzZqT05tQVhBYWtXSFNRTHJvR3Z4eWN4M1dDL1lNdEQrRWh6VGlFaTZBaEJaMGZsR1AzL01SOVA4MXhiMWdEVDUrcXciLCJtYWMiOiJhN2QwZWIwYTBiMWIzMTZiZDIyNjJiMmFkMzNjMTljMDNkYjU0ZjRmODZkNjUwNDRlY2M2ZjhiOGE0M2M4ZmFjIiwidGFnIjoiIn0%3D; expires=Fri, 21 Feb 2025 22:07:00 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6IkF6eXRzVVpudkNpSnBjNzEzOTFvdmc9PSIsInZhbHVlIjoiSWxIWS92MjJRRGhhd1ZaYUh0NHEzYmJnZXRxc3M0UmJ5dGlJQ1ROSlNLZjJuZUxRQVkyM1I3QVJRdUVJNzZqT05tQVhBY" 1 => "alphaeurekaselectnet_session=eyJpdiI6IjkxMVp3SGFRWk4vT2g5ZE9FZjNheGc9PSIsInZhbHVlIjoibHd3eExHWjQweWg3WFpIWGs4ajJHVnQ4eXczblk2OUlPclVJcURydkgrd1NiUXNFZS9sdkgxeDhCSWEraEFzU1pVekFYbExHSCtKcmhGY0hBWklkb3JwajByRjltbzVNdmNLTllHTE9CbitFWk9IZ1RvdUJUQ2l4eHFuSmZ3bUIiLCJtYWMiOiI2MGZiNjk2ZThmZTMxYTdjNDdiNDc2Y2YxYTM3MTUyMzZiZGFlZmU5MWZiNTBlZDAxNDExZjk4NWQ5MzA4NDNiIiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6IjkxMVp3SGFRWk4vT2g5ZE9FZjNheGc9PSIsInZhbHVlIjoibHd3eExHWjQweWg3WFpIWGs4ajJHVnQ4eXczblk2OUlPclVJcURydkgrd1NiUXNFZS9sdkgxeDh" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IkF6eXRzVVpudkNpSnBjNzEzOTFvdmc9PSIsInZhbHVlIjoiSWxIWS92MjJRRGhhd1ZaYUh0NHEzYmJnZXRxc3M0UmJ5dGlJQ1ROSlNLZjJuZUxRQVkyM1I3QVJRdUVJNzZqT05tQVhBYWtXSFNRTHJvR3Z4eWN4M1dDL1lNdEQrRWh6VGlFaTZBaEJaMGZsR1AzL01SOVA4MXhiMWdEVDUrcXciLCJtYWMiOiJhN2QwZWIwYTBiMWIzMTZiZDIyNjJiMmFkMzNjMTljMDNkYjU0ZjRmODZkNjUwNDRlY2M2ZjhiOGE0M2M4ZmFjIiwidGFnIjoiIn0%3D; expires=Fri, 21-Feb-2025 22:07:00 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6IkF6eXRzVVpudkNpSnBjNzEzOTFvdmc9PSIsInZhbHVlIjoiSWxIWS92MjJRRGhhd1ZaYUh0NHEzYmJnZXRxc3M0UmJ5dGlJQ1ROSlNLZjJuZUxRQVkyM1I3QVJRdUVJNzZqT05tQVhBY" 1 => "alphaeurekaselectnet_session=eyJpdiI6IjkxMVp3SGFRWk4vT2g5ZE9FZjNheGc9PSIsInZhbHVlIjoibHd3eExHWjQweWg3WFpIWGs4ajJHVnQ4eXczblk2OUlPclVJcURydkgrd1NiUXNFZS9sdkgxeDhCSWEraEFzU1pVekFYbExHSCtKcmhGY0hBWklkb3JwajByRjltbzVNdmNLTllHTE9CbitFWk9IZ1RvdUJUQ2l4eHFuSmZ3bUIiLCJtYWMiOiI2MGZiNjk2ZThmZTMxYTdjNDdiNDc2Y2YxYTM3MTUyMzZiZGFlZmU5MWZiNTBlZDAxNDExZjk4NWQ5MzA4NDNiIiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6IjkxMVp3SGFRWk4vT2g5ZE9FZjNheGc9PSIsInZhbHVlIjoibHd3eExHWjQweWg3WFpIWGs4ajJHVnQ4eXczblk2OUlPclVJcURydkgrd1NiUXNFZS9sdkgxeDh" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "QokpgNTeqvLARmGNqrNwC940fymV7ijDo2vMlrDv" "uc_cart_id" => "6eb5c5fff8bd405e39e21d6c0b08edff" "_previous" => array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/20268" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-19 10:07:00GET/chapter/20268112192