Abstract
Theranostics, a dual strategy, helps in better tumor imaging, the
biodistribution of drugs (the ability to direct therapeutic agents to the tumor site), and
understanding the progress and effectiveness of therapy. Theranostics is an emerging
technology for the diagnosis and management of brain tumors which differ from
peripheral tumors in several ways because of their complexity in the genesis of
oncogenes. Several factors must be considered for successful brain tumor-targeted drug
delivery. Nanotheranostics for brain cancer therapies have been identified now, and
polymeric nanoparticles (PNP) are one of the most efficient and promising
nanotechnological platforms. They can be utilized as a new imaging method to
optimize chemotherapeutic drug delivery into brain tumors while reducing the drug's
dissemination and toxicity in healthy people. Smart carriers and theranostic
nanoparticles can diagnose, deliver, and track the therapeutic response synchronized.
This chapter gives an insight into superparamagnetic, ultrasound-triggered radionuclide
bearing, and fluorescent PNPs as potential theranostic approaches for brain tumor
management.