Abstract
The bifunctional taxoid-colchicinoid hybrids were synthesised and evaluated in assays of cytotoxicity and tubulin assembly/disassembly. All compounds showed a high degree of cytotoxicity.
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Cite this chapter as:
Daniele Passarella, Alessandra Giardini, Giordano Lesma, Alessandra Silvani, Bruno Danieli ;Nature as Source and Inspiration for the Synthesis of New Anticancer Drugs, Frontiers in Natural Product Chemistry (2005) 1: 51. https://doi.org/10.2174/978160805212710501010051
DOI https://doi.org/10.2174/978160805212710501010051 |
Print ISSN 1574-0897 |
Publisher Name Bentham Science Publisher |