Abstract
Carbon nanostructures such as carbon nanotubes, graphene, graphene oxide
and their derivatives, have been recognized in biomedicine and drug delivery, due to
their outstanding optical, mechanical, thermal, and electrical characteristics. Carbon
nanostructures/ polymer composites with various active and functional groups provide
many binding sites for inorganic/organic species and biomolecules and are described as
favorable candidates to label and drag different drugs, genes, proteins and therapeutic
molecules. This chapter focuses on studies about the deployment of nanostructures/
polymer composites, for efficient drug delivery, especially localized controlled
drug/gene delivery systems (LCDDS). Effects of various parameters and features,
including composite microstructures, hydrophobicity and hydrophilicity of composites,
glass transition and polymer matrix molecular weight, on LCDDS are fully examined
and discussed.
Keywords: Carbon nanostructure, Carbon nanotube, Composite, Graphene, Polymer, Local drug delivery.