NEOPLASIA and FERTILITY

Breast Cancer and Pregnancy

Author(s): P. Zola, C. Macchi*, G. Parpinel, B. Masturzo, M. Laudani, E. Potenza and M. Mitidieri

Pp: 86-105 (20)

DOI: 10.2174/9789815050141122010006

* (Excluding Mailing and Handling)

Abstract

 The association between breast cancer and pregnancy is defined as detecting breast cancer during pregnancy or within one year after delivery. The diagnosis is often difficult and delayed. It is based on clinical examination, radiological exams (ultrasound and/or RM) and biopsy of the suspected lesion. The staging examinations should be performed only if any change in therapeutic decisions or clinical practice could be made or in the presence of a high risk of distant metastases. The treatment includes surgery, radiotherapy, chemotherapy, hormonal therapy and molecular targeted therapy, and it should be as close as possible with the standard protocols of non-pregnant patients and should be discussed with a multidisciplinary team. It is important to start the treatment as soon as possible, with the exception of term pregnant patients, for whom it can be postponed after delivery. The major fetal complications seem to be related to prematurity, and the type of delivery depends on obstetrics indication. The delivery should be planned at least three weeks after the infusion of chemotherapy, and the treatment generally could be restarted one week after the cesarean section and immediately after a vaginal delivery. The apparent poor outcome in pregnant women can be explained by the delayed diagnosis and/or treatment and the biological characteristics of the tumor (often of high grade and triple negative). Finally, when the treatment is planned, reproductive counseling should always be proposed to young patients immediately after diagnosis in order to plan the best fertility preservation strategies


Keywords: Biopsy, BRCA mutation, Breast cancer, Breastfeeding, Chemotherapy, Delivery, Fertility preservation, Histological type, hormone therapy, Lymph nodes metastases, Magnetic resonance, Mammography, Multidisciplinary team, Pregnancy, Prematurity, Prenatal care, Radiotherapy, Surgery, Survival, Ultrasound.

Related Journals
Related Books
© 2025 Bentham Science Publishers | Privacy Policy
Request history8.2.27PHP Version173msRequest Duration26MBMemory UsageGET chapter/{id}/{param?}Route
  • warninglog[23:26:58] LOG.warning: Optional parameter $id declared before required parameter $request is implic...
  • Booting (91.09ms)time
  • Application (81.65ms)time
  • 1 x Booting (52.73%)
    91.09ms
    1 x Application (47.27%)
    81.65ms
    12 templates were rendered
    • ebook.chapter_detailschapter_details.blade.php#?blade
    • layouts.chapter_header_sectionchapter_header_section.blade.php#?blade
    • ebook.chapter_top_bannerchapter_top_banner.blade.php#?blade
    • ebook.chapter_bottom_bannerchapter_bottom_banner.blade.php#?blade
    • ebook.ebook_right_bannerebook_right_banner.blade.php#?blade
    • includes.inc_related_journalsinc_related_journals.blade.php#?blade
    • includes.inc_related_ebooksinc_related_ebooks.blade.php#?blade
    • layouts.appapp.blade.php#?blade
    • layouts._login_access_login_access.blade.php#?blade
    • layouts._header_header.blade.php#?blade
    • layouts._main_menu_main_menu.blade.php#?blade
    • layouts._footer_menu_footer_menu.blade.php#?blade
    uri
    GET chapter/{id}/{param?}
    middleware
    web, check_user_access
    controller
    App\Http\Controllers\ChapterController@GetChapterDetails
    namespace
    App\Http\Controllers
    where
    as
    chapter
    file
    app/Http/Controllers/ChapterController.php:1350-1704
    19 statements were executed25.7ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('873346344','',1,1739834819,1739834819) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1739834819
      950μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('873346344','/chapter/17872',1,1739834819,1739834819)
      170μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 873346344 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 873346344) limit 1
      14.42msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 873346344
      • 1: 873346344
      • 2: 873346344
      • 3: 873346344
      • 4: 873346344
      • 5: 873346344
      • 6: 873346344
      • 7: 873346344
      • 8: 873346344
      • 9: 873346344
      • 10: 873346344
      • 11: 873346344
      • 12: 873346344
      • 13: 873346344
      • 14: 873346344
      • 15: 873346344
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • select * from `chapter` where `chapter_id` = '17872' limit 1
      270μsalphaeurekaselec_live_10_06_2022ChapterController.php#1406
      Bindings
      • 0: 17872
      Backtrace
      • 16. app/Http/Controllers/ChapterController.php:1406
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`chapter_id` = '17872' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      800μsalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 17872
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ChapterController.php:1411
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `keywords` where `chapter_id` = '17872'
      300μsalphaeurekaselec_live_10_06_2022ChapterController.php#1415
      Bindings
      • 0: 17872
      Backtrace
      • 15. app/Http/Controllers/ChapterController.php:1415
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select * from `ebook` where `ebook_id` = 1051 limit 1
      230μsalphaeurekaselec_live_10_06_2022ChapterController.php#1430
      Bindings
      • 0: 1051
      Backtrace
      • 16. app/Http/Controllers/ChapterController.php:1430
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select count(*) as aggregate from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `e`.`ebook_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=1051) and se.ebook_id!=1051 and v.ebook_status='1'
      2.83msalphaeurekaselec_live_10_06_2022Subject.php#238
      Backtrace
      • 16. app/Models/Subject.php:238
      • 17. app/Http/Controllers/ChapterController.php:1434
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select distinct v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `e`.`ebook_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=1051) and se.ebook_id!=1051 and v.ebook_status='1' limit 10 offset 0
      760μsalphaeurekaselec_live_10_06_2022Subject.php#238
      Backtrace
      • 14. app/Models/Subject.php:238
      • 15. app/Http/Controllers/ChapterController.php:1434
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as aggregate from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=1051)
      420μsalphaeurekaselec_live_10_06_2022Subject.php#255
      Backtrace
      • 16. app/Models/Subject.php:255
      • 17. app/Http/Controllers/ChapterController.php:1435
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select distinct j.nid as journal_nid,j.title,j.subtitle,j.issn,j.eissn,j.keyword,sj.journal_id,j.image_file_name,j.flyer_link from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=1051) limit 10 offset 0
      460μsalphaeurekaselec_live_10_06_2022Subject.php#255
      Backtrace
      • 14. app/Models/Subject.php:255
      • 15. app/Http/Controllers/ChapterController.php:1435
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `e`.*, `a`.*, `y`.`year`, `e`.`ebook_volume_id` as `ebook_volume_id`, `a`.`ebook_volume_id` as `ebk_vol_id`, `e`.`ebook_id` as `ebk_ebook_id` from `ebook_volume` as `e` left join `author` as `a` on `e`.`ebook_volume_id` = `a`.`ebook_volume_id` left join `year` as `y` on `y`.`id` = `e`.`year_id` where `e`.`ebook_volume_id` = 3410 and `e`.`is_uploaded` = 1
      480μsalphaeurekaselec_live_10_06_2022EbookVolume.php#271
      Bindings
      • 0: 3410
      • 1: 1
      Backtrace
      • 13. app/Models/EbookVolume.php:271
      • 14. app/Http/Controllers/ChapterController.php:1438
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) rcd from `ebook_volume` where `ebook_id` = 1051 and ebook_volume_id <> 3410 limit 1
      260μsalphaeurekaselec_live_10_06_2022EbookVolume.php#999
      Bindings
      • 0: 1051
      Backtrace
      • 14. app/Models/EbookVolume.php:999
      • 15. app/Http/Controllers/ChapterController.php:1462
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from ebook_access where content_type_id = '17872' and content_type = 'c' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      290μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1465
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from ebook_access where content_type_id = '3410' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      250μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1478
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 873346344 and j.to_ip >=873346344 )) and ((j.from_date <= 1739834819 and j.to_date >= 1739834819 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3410) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 873346344 and j.to_ip >=873346344 )) and ((j.from_date <= 1739834819 and j.to_date >= 1739834819 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3410) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 873346344 and j.to_ip >=873346344 )) and ((j.from_date <= 1739834819 and j.to_date >= 1739834819 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 3410)
      640μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1518
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 873346344 and j.to_ip >=873346344 )) and ((j.from_date <= 1739834819 and j.to_date >= 1739834819 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 17872) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 873346344 and j.to_ip >=873346344 )) and ((j.from_date <= 1739834819 and j.to_date >= 1739834819 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 17872) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 873346344 and j.to_ip >=873346344 )) and ((j.from_date <= 1739834819 and j.to_date >= 1739834819 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 17872)
      790μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1549
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 3410 and `b`.`banner_from_date` <= 1739834819 and `b`.`banner_to_date` >= 1739834819 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.17msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 3410
      • 3: 1739834819
      • 4: 1739834819
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='76505e6b0b3b53dc656a808183c361ad'
      210μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Keywords
    20Keywords.php#?
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        n6GucE1tcGaaXu2EqsBA6N92BPBiSxfzZALNTXgv
        uc_cart_id
        76505e6b0b3b53dc656a808183c361ad
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/17872" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/17872
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:17 [ "x-https" => array:1 [ 0 => "1" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] "priority" => array:1 [ 0 => "u=0, i" ] "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6IjgwY3RWQlZUTE1rNTBzMFQzVzFQbXc9PSIsInZhbHVlIjoiYVBybTV5ZThCQVVnM1lmc1hYZTZQTnpYSjJuS0pOZlpUOVMreVpPS0Q1YkFTeUJFMWFwbzM0TWlEVlhWTEYxYiIsIm1hYyI6Ijg4NzRiZWMxMjgyN2YyNTFkYzkwMmFkZDFmNDc2ZGFjMGY4MTJhODlkN2ZmM2U0NDZmODMyNjBmOTM3MmRiNGEiLCJ0YWciOiIifQ%3D%3D; XSRF-TOKEN=eyJpdiI6IjIxNU5veEl0WS9BaGJseWZqRFRCbmc9PSIsInZhbHVlIjoic0dyQmJYUmZWSTlVMWl6ZVZyM1c5eUNyN0l0bmZiaTdXekRKOTh1NFo4YUM4Z3UzUGNhdlpPS2l5UFg2a0g2Zkh5RzJqS215UEE4QmpSMlF1cTJFSUhDZCtxc0kyUm5VSmUxWFlRRHBiTWZnY1NGZTZPYTlBZjhGYzBUYmZGUXciLCJtYWMiOiIzNGEyYzZkMDM4OWI4OTg4ZTU5ZTM3NzAwNmE0NzQxYzhmNTM1OGJiYjg2YzNiNWZiOGNjZWE5ZjM1MjgwZjQyIiwidGFnIjoiIn0%3D; alphaeurekaselectnet_session=eyJpdiI6IkxBUU5LTzFEeWtQbG9pc0tlTHZDTkE9PSIsInZhbHVlIjoiU2ZhTEM2VHNEVTZNNnhSTVNJNGF2VE1GZE14NXBVN2JjSmluOThpUmszd0lGSGhEc3NxYUxzMUpvK2FFTENTc3B0d0Ewc3FhcFlnMGVCbUZFUEY1Njg3cHBRUUoxRlRxSjJSQ2pUSXBvdkJRMGFNUzlKQ2xoenhkRFh2QzY4Mk8iLCJtYWMiOiIxNDY5OTI0YWI4M2Y5YzU3NjAzNTMwMDIyNzgyMzVjYmU3MzY5MDZjNjc1Y2YxMjJiZmEyNmVmMGE4MTNkMWQxIiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6IjgwY3RWQlZUTE1rNTBzMFQzVzFQbXc9PSIsInZhbHVlIjoiYVBybTV5ZThCQVVnM1lmc1hYZTZQTnpYSjJuS0pOZlpUOVMreVpPS0Q1YkFTeUJFMWFwbzM0TWlEVlhWTEYxYiIs" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate, br, zstd" ] "sec-fetch-dest" => array:1 [ 0 => "document" ] "sec-fetch-user" => array:1 [ 0 => "?1" ] "sec-fetch-mode" => array:1 [ 0 => "navigate" ] "sec-fetch-site" => array:1 [ 0 => "none" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "sec-ch-ua-platform" => array:1 [ 0 => ""Windows"" ] "sec-ch-ua-mobile" => array:1 [ 0 => "?0" ] "sec-ch-ua" => array:1 [ 0 => ""HeadlessChrome";v="129", "Not=A?Brand";v="8", "Chromium";v="129"" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] ]
        request_cookies
        0 of 0
        array:3 [ "wayfindertarget" => null "XSRF-TOKEN" => "n6GucE1tcGaaXu2EqsBA6N92BPBiSxfzZALNTXgv" "alphaeurekaselectnet_session" => "Ew2dNBjveHfYg68QoCujSWfmaCovNo0idGJXk9yM" ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Mon, 17 Feb 2025 23:26:59 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6ImxDMGJsdVFmVVNtWDQ3US9kNlJqSUE9PSIsInZhbHVlIjoiUUh2TVlhUzNBUWpZYXFMRE4yazZaS01laUFJdzZ4L1JqNmExSkJFN3RaTkplZ1N2bnh4RXNHQlVqcDNaRFdtMDN4VE04azJ4Sm5lMlo4QUUvSElXTnYyS2hKeFdOMGM4YXNlMmhhbXBMQ3U2b21LOU5GTlZEazVQYXB4MTVSaEsiLCJtYWMiOiIzZWQyMWJhN2VkM2Q3OTI1MWI4ODMzN2Q3N2Q4ZjRkMDdmZDc5MTU2OWQ4NGZlNGQ5M2I1MzhmNzEwYTYxYWQ5IiwidGFnIjoiIn0%3D; expires=Thu, 20 Feb 2025 11:26:59 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6ImxDMGJsdVFmVVNtWDQ3US9kNlJqSUE9PSIsInZhbHVlIjoiUUh2TVlhUzNBUWpZYXFMRE4yazZaS01laUFJdzZ4L1JqNmExSkJFN3RaTkplZ1N2bnh4RXNHQlVqcDNaRFdtMDN4VE04a" 1 => "alphaeurekaselectnet_session=eyJpdiI6Ik1UZ1FuM002MUF3SVRpQkRhQnFKc2c9PSIsInZhbHVlIjoidnllYVFrSUsrYzJ5VDlzWENDZmNYaGtqZ3A2VjBZSzZTdThPZ0NoVG9kT1dBS2Z5U1Mxb0ZkeTNQVHBvb2dFNlFkRWdFd3lLMGFVSnJOSlFvdmxPZGhRUGlhaUlkZ0d4dkw4TXpmakhTTHY1TWRrUjFtMjJxUTJkV0xjL0p3VUwiLCJtYWMiOiI2NjBhMzUwNWRiZjUzZTdlOGMxZjg3MGQwMDExNjZmNGEwN2RjNjk4NzZiMGY3ZWVhZjkzZDY5NjA1Mjg0YTYwIiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6Ik1UZ1FuM002MUF3SVRpQkRhQnFKc2c9PSIsInZhbHVlIjoidnllYVFrSUsrYzJ5VDlzWENDZmNYaGtqZ3A2VjBZSzZTdThPZ0NoVG9kT1dBS2Z5U1Mxb0ZkeTN" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6ImxDMGJsdVFmVVNtWDQ3US9kNlJqSUE9PSIsInZhbHVlIjoiUUh2TVlhUzNBUWpZYXFMRE4yazZaS01laUFJdzZ4L1JqNmExSkJFN3RaTkplZ1N2bnh4RXNHQlVqcDNaRFdtMDN4VE04azJ4Sm5lMlo4QUUvSElXTnYyS2hKeFdOMGM4YXNlMmhhbXBMQ3U2b21LOU5GTlZEazVQYXB4MTVSaEsiLCJtYWMiOiIzZWQyMWJhN2VkM2Q3OTI1MWI4ODMzN2Q3N2Q4ZjRkMDdmZDc5MTU2OWQ4NGZlNGQ5M2I1MzhmNzEwYTYxYWQ5IiwidGFnIjoiIn0%3D; expires=Thu, 20-Feb-2025 11:26:59 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6ImxDMGJsdVFmVVNtWDQ3US9kNlJqSUE9PSIsInZhbHVlIjoiUUh2TVlhUzNBUWpZYXFMRE4yazZaS01laUFJdzZ4L1JqNmExSkJFN3RaTkplZ1N2bnh4RXNHQlVqcDNaRFdtMDN4VE04a" 1 => "alphaeurekaselectnet_session=eyJpdiI6Ik1UZ1FuM002MUF3SVRpQkRhQnFKc2c9PSIsInZhbHVlIjoidnllYVFrSUsrYzJ5VDlzWENDZmNYaGtqZ3A2VjBZSzZTdThPZ0NoVG9kT1dBS2Z5U1Mxb0ZkeTNQVHBvb2dFNlFkRWdFd3lLMGFVSnJOSlFvdmxPZGhRUGlhaUlkZ0d4dkw4TXpmakhTTHY1TWRrUjFtMjJxUTJkV0xjL0p3VUwiLCJtYWMiOiI2NjBhMzUwNWRiZjUzZTdlOGMxZjg3MGQwMDExNjZmNGEwN2RjNjk4NzZiMGY3ZWVhZjkzZDY5NjA1Mjg0YTYwIiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6Ik1UZ1FuM002MUF3SVRpQkRhQnFKc2c9PSIsInZhbHVlIjoidnllYVFrSUsrYzJ5VDlzWENDZmNYaGtqZ3A2VjBZSzZTdThPZ0NoVG9kT1dBS2Z5U1Mxb0ZkeTN" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "n6GucE1tcGaaXu2EqsBA6N92BPBiSxfzZALNTXgv" "uc_cart_id" => "76505e6b0b3b53dc656a808183c361ad" "_previous" => array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/17872" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-17 23:26:59GET/chapter/178721121922