Emerging Trends in Bioinformatics for Breast Cancer Molecular Research

Abstract

Applications of bioinformatic methods and high-throughput sequencing techniques have increased exponentially over the last decade, transforming the way we understand complex malignancies such as breast cancer. In this chapter, an overview of recent advances in molecular research in breast cancer using emerging bioinformatics methods is presented. Learnings from scientific studies that have successfully integrated and interpreted massive amounts of data generated from various platforms (multi-omics data) using bioinformatics approaches are also outlined. Additionally, pan-cancer studies that help identify the differences and commonalities across multiple cancers are reviewed. We also discuss bioinformatics applications that transform the way we decipher the OncoGenomic landscape of breast cancer. Finally, this study also summarizes current publicly available bioinformatics tools and databases for breast cancer research.

Keywords: Bioinformatics, Genomics, High-throughput sequencing, Multiomics, Next-generation sequencing, Pan-cancer analysis, Transcriptomics.

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