Unveiling Distinguished Methodologies for the Diagnosis of COVID-19

As a result of its broad clinical presentation – from asymptomatic infection

to severe acute respiratory syndrome (SARS), COVID-19 has emerged as a

broadcasting pandemic worldwide. A viral test tells you if you have a current infection.

Confirmation of a high-risk for COVID-19 patient has been prioritized in containment

efforts. The current diagnostic methods for COVID-19 rely on higher sensitivity,

specificity, and faster results. Two types of diagnostic methods have been considered:

nucleic acid amplification tests and serological tests. Whereas the first one confirms

infection, the second might disclose outcomes from past infection or immunological

parameters left by the contamination. Here we collect emerging understanding of the

underlying role of molecular and serological tests incorporated in the routine of

COVID-19 diagnosis and outline some features related to the methodologies.

Keywords: Antibodies, Antigens, COVID-19, Diagnosis, Diagnostic methods, Immunological tests, Immunoenzymatic assay, Isothermal Amplification, Molecular tests, Nucleic Acid Assays Methods, Outbreak, Pandemic, Point of Care Test Devices, Rapid test, RNA sequencing, RT–ERA, RT-qPCR, RTLAMP, SARS-CoV2, Serological tests.

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