Abstract
The chapter outlines the trends in the rapid development of
biofunctionalized hybrid nanomaterials for application as immune sensors to detect
biomarkers, thehallmarks of diseases. Biofunctioanalized advanced materials
incorporate biological macromolecules/biomaterials with high specificity and
selectivity, such as proteins with unique binding properties which are combined with
the electronic, optical or photonic properties of nanostructures, enabling them to
function as sensors. Functionalization materialises due to similarity in dimension scale
allowing functional coupling leading to an effective signal transduction in these
sensors. A variety of nano objects metals, carbon nanotubes are coupled with
proteins/immunoglobulins or antigens to yield biofunctionalized advanced materials
leading to the development of promising novel immune biosensors with many
advanced features, like ergonomic, time saving, sensitivity, point-of-care cost
economy, feasibility and reproducibility.
Keywords: Antibody, Antigen, Diagnostics, Functionalization, Immunosenors, Nanomaterials.
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