Advanced Sensor Materials for Drug Analysis

Nanomaterials play an important role in the fabrication of many devices and

modified materials, due to their unique properties, such as large surface area/volume

ratio, conductivity and high mechanical strength. In the present chapter, the

applicability of nanomaterials in drug analysis is well investigated. The recent trends in

the development of the electrochemical sensor platforms based on state-of-the-art

nanomaterials such as metal nanoparticles, metal oxide nanoparticles, carbon

nanomaterials, conducting polymer and nanocomposites are discussed. The unique

synthetic approaches, properties, integration, strategies, selected sensing applications

and future prospects of these nanostructured materials for the design of advanced

sensor platforms are also highlighted. Various kinds of functional nanocomposites have

led to the enhancement in voltammetric response due to drug - nanomaterials

interaction at the modified electrode surface. So, different mechanisms for the

extraordinary and unique electrocatalytic activities of such nanomaterials will be

highlighted. Potential applications of electrochemical sensor platforms based on

advanced functional nanomaterials for drug analysis are presented. High sensitivity and

selectivity, fast response, and excellent durability in biological media are all critical

aspects which will also be addressed. It is expected that the chemically modified

electrodes with various nanomaterials can be easily miniaturized and used as wearable,

portable and user friendly devices. This will pave the way for in-vivo onsite real

monitoring of single as well as multi-component pharmaceutical compounds. The

significant development of the nanomaterials based electrochemical sensor platforms is

giving rise to a new impetus of generating novel technologies for securing human and

environmental safety.

Keywords: Analysis of drug, Biological fluids, Carbon nanotubes, Conducting polymer, Electrochemical sensor, Graphene, Hybrid nanostructure, Imprinted polymers, Metal nanoparticles, Metal oxide nanoparticles.

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