Abstract
The ability to extract oxygen from the environment and deliver it to each cell of the multicellular organism through metabolism in time was the main development of organisms during evolution. The life of living organisms is absolutely dependent on oxygen supplementation for respiration, a process by which cells produce ATP to obtain energy energy from controlled reactions of hydrogen with oxygen to produce water. Depending on cell type, function and biological state, cells have a broad range in oxygen utilization. Here there is evidence on the considerable increase of reactive oxygen species-ROS caused by metabolic alterations, as response the low levels of oxygen available-hypoxia that occur in human cells.
Keywords: Glucose Regulating Proteins (GRPs), Heat Shock Proteins (HSPs), Hipoxic Conditions, Hypoxia-Associated Proteins (HAPS) and Oxygen Regulating Proteins (ORPs), Oxygen Consumption Rates (OCRs), Oxygen Levels in the Blood, Respiratory Insufficiency.