Abstract
This chapter proposes a brief description of the Role of Bioinformatics in the Post-Genomic Era; Digital Sequence Repositories; From the World of 1D to the era of 3D (Protein Structures); Functional Genomics; Sequence Alignment, Phylogeny, and concept of gene evolution; Sequence and structural alignment; Genomics of personalized medicine; CADD: Computer-Aided Drug Designing; Big Data Analysis; Responsible Genomic data sharing.
Keywords: Alignment, Big data, CADD, Digital Sequence Repositories, Functional Genomics, Protein Structures.