Abstract
Precision nanomedicine based on advanced diagnosis by personalized analysis with, for example, the incorporation of genomics and specific biomarker tracking have allowed faster diagnosis and application of treatments. With controlledsize cargo nanoparticles, potential applications were also devised for targeted drug delivery, in addition to new enzymatic approaches addressing targeted delivery for targeted DNA repairs. Another novel gene therapy is also discussed. Moreover, we show, for personalized drug assay tests, how design-led to bioassays within microfluidic four-organ-chip devices in order to evaluate compatibilities and effects according to the nature and response of the organism.
Keywords: CRISPR-Cas9, Drug delivery system, Genomics, Gene therapy, Implantable microdevice, Lab-on particle, Precision nanomedicine, Personalized medicine.
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