A Comprehensive Guide to Nanoparticles in Medicine

Recent Progress of Nanoparticles Used in the Diagnosis of Different Types of Diseases

Author(s): Rituparna Acharya * .

Pp: 39-56 (18)

DOI: 10.2174/9781681088358121010006

* (Excluding Mailing and Handling)

Abstract

Nanoparticles used in the detection of biomolecules are being possibly used due to their physical and chemical properties that optimize them with unique characteristics. These properties enable the diagnosis of several disease conditions to make them available for treatment. This study is intended to discuss the emergence of this area and help the researchers in further progress in this field.

This study discusses the disadvantages of the use of currently available methods for diagnostic purposes. It also examines the advantages of the use of nanoparticles in this field of study. This study reviews the properties of metallic nanoparticles including gold and silver, and also quantum dot, silica nanoparticles, etc.

Nanotechnology has extended the limitation of the current diagnostic procedures. The potential of using nanoparticles in the diagnosis of diseases is unlimited. Safety study is needed for in vivo uses. Nanobiotechnology in clinical uses will play a valuable role in the future development of nanomedicines also.


Keywords: Colorimetric detection, Electrochemical-based detection, ELISA, Emission-based detection, FLISA, Fluorescence based detection, FRET, Gold nanoparticle, Magnetic-based detection, MEF, Microarray detection, MRI, NMR, Plasmonics-based detection, Quantum dot, Quenching, SEIRF, SERS, Silica nanoparticle, Silver nanoparticle.

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      • 13. app/Models/UserAccess/UserAccess.php:1266
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      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51399716 and j.to_ip >=51399716 )) and ((j.from_date <= 1739834608 and j.to_date >= 1739834608 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 15031) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51399716 and j.to_ip >=51399716 )) and ((j.from_date <= 1739834608 and j.to_date >= 1739834608 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 15031) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 51399716 and j.to_ip >=51399716 )) and ((j.from_date <= 1739834608 and j.to_date >= 1739834608 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 15031)
      540μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1549
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 3081 and `b`.`banner_from_date` <= 1739834608 and `b`.`banner_to_date` >= 1739834608 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.35msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 3081
      • 3: 1739834608
      • 4: 1739834608
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='cd40582b2150d48a8a658460c1d80c2a'
      260μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Keywords
    20Keywords.php#?
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        zsArVsQ96x6peanjLpSpbWfXRbeEg3z1jNafbREp
        uc_cart_id
        cd40582b2150d48a8a658460c1d80c2a
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/15031" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/15031
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
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        request_cookies
        0 of 0
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        response_headers
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        ClearShow all
        Date ↕MethodURLData
        #12025-02-17 23:23:28GET/chapter/150311121922