Oral Infections and Cardiovascular Disease

Dental Infections and Cardiovascular Disease - The Early Findings

Author(s): Kimmo Mattila

Pp: 3-7 (5)

DOI: 10.2174/978160805232511101010003

* (Excluding Mailing and Handling)

Abstract

The clinical entity “coronary heart disease (CHD)” comprises two major components – atherosclerosis (AS) of the coronary arteries and acute thrombosis that occasionally occurs superimposed on an atherosclerotic artery wall, causing various types of acute coronary syndromes (ACS) like acute myocardial infarction (AMI). As CHD is a major cause of mortality and morbidity in the Western societies, massive research efforts have been invested in it. It has become clear e.g. that the triggering factors for acute manifestations of CHD are not identical to the slow-acting, classic risk factors for coronary AS. The large impact of hypercholesterolemia, hypertension and smoking on the development of CHD has been established already some decades ago. Yet they do no explain all clinical and epidemiological features of CHD. These major CVD risk factors have dominated the research filed, and it has not always been easy for other potential risk factors to receive attention and research funding.

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      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1478
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
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      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1518
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316245611 and j.to_ip >=316245611 )) and ((j.from_date <= 1740472923 and j.to_date >= 1740472923 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 1497) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316245611 and j.to_ip >=316245611 )) and ((j.from_date <= 1740472923 and j.to_date >= 1740472923 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 1497) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316245611 and j.to_ip >=316245611 )) and ((j.from_date <= 1740472923 and j.to_date >= 1740472923 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 1497)
      1msalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1549
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 894 and `b`.`banner_from_date` <= 1740472923 and `b`.`banner_to_date` >= 1740472923 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.54msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 894
      • 3: 1740472923
      • 4: 1740472923
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='11ca9b4b539f6763917dd6bdceab6ff5'
      10.99msalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Keywords
    1Keywords.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        M1ETwM6Tpj0fmyTydedoPUxO4LCZHIs3k3w6LP2q
        uc_cart_id
        11ca9b4b539f6763917dd6bdceab6ff5
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/1497" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/1497
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
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        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Tue, 25 Feb 2025 08:42:03 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IlU5NlRKQjY3cmw5TG5KUk9LT0U4UHc9PSIsInZhbHVlIjoiTkVyaUlscG1DemFGc1pmWkIzS3ZLZG1iamJYazAxWHBRSi92amdiVytXOGY4SE5iL3RHWHZiandrSVVyYXlDUzd0SjhNTTg5cnl1V3RBRmwzWEJzQW9BTTRqL3hJamp1ampmNGdhOFhJOE8yZW54ZVo0MUFFNGQ3bi83dHd0M3YiLCJtYWMiOiI3NzNkN2JkZGVjNmYwNjY1ZTE5NGY3MzcwOGNhZWQ1YmZkYWI0NTE1ZWNjOGMxN2NjNzhkNWY1ZDFjYjdmNDU3IiwidGFnIjoiIn0%3D; expires=Thu, 27 Feb 2025 20:42:03 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6IlU5NlRKQjY3cmw5TG5KUk9LT0U4UHc9PSIsInZhbHVlIjoiTkVyaUlscG1DemFGc1pmWkIzS3ZLZG1iamJYazAxWHBRSi92amdiVytXOGY4SE5iL3RHWHZiandrSVVyYXlDUzd0SjhNT" 1 => "alphaeurekaselectnet_session=eyJpdiI6IjN3YTBuNjZvOENDNElsUXJoaUp3K3c9PSIsInZhbHVlIjoidlE3NEhMeVpPdFJmdEZQVjJ3dlJCL2tEdWF4OHFPSHpCeWJBT0IxTU9XWXlXTHI2NUpzZC9YeFB0OU8yK2IybFFPMGRVRW9teHRBd083T3Rkd3hJNk1UYmpmb0puZzJqc2NVQ3JkRCsreUZDT3RjQys1dmlsUUhQcjdiNXp1UysiLCJtYWMiOiJkMjY4ZTk1ZDRkMTI3NjI4ZTdkMmFlNGYzMTQ2ZGJkOTM0N2M3ZmE0NzRiYzg1NTgzMTA3MGQwY2FhNTRjZjQ3IiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6IjN3YTBuNjZvOENDNElsUXJoaUp3K3c9PSIsInZhbHVlIjoidlE3NEhMeVpPdFJmdEZQVjJ3dlJCL2tEdWF4OHFPSHpCeWJBT0IxTU9XWXlXTHI2NUpzZC9YeFB" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IlU5NlRKQjY3cmw5TG5KUk9LT0U4UHc9PSIsInZhbHVlIjoiTkVyaUlscG1DemFGc1pmWkIzS3ZLZG1iamJYazAxWHBRSi92amdiVytXOGY4SE5iL3RHWHZiandrSVVyYXlDUzd0SjhNTTg5cnl1V3RBRmwzWEJzQW9BTTRqL3hJamp1ampmNGdhOFhJOE8yZW54ZVo0MUFFNGQ3bi83dHd0M3YiLCJtYWMiOiI3NzNkN2JkZGVjNmYwNjY1ZTE5NGY3MzcwOGNhZWQ1YmZkYWI0NTE1ZWNjOGMxN2NjNzhkNWY1ZDFjYjdmNDU3IiwidGFnIjoiIn0%3D; expires=Thu, 27-Feb-2025 20:42:03 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6IlU5NlRKQjY3cmw5TG5KUk9LT0U4UHc9PSIsInZhbHVlIjoiTkVyaUlscG1DemFGc1pmWkIzS3ZLZG1iamJYazAxWHBRSi92amdiVytXOGY4SE5iL3RHWHZiandrSVVyYXlDUzd0SjhNT" 1 => "alphaeurekaselectnet_session=eyJpdiI6IjN3YTBuNjZvOENDNElsUXJoaUp3K3c9PSIsInZhbHVlIjoidlE3NEhMeVpPdFJmdEZQVjJ3dlJCL2tEdWF4OHFPSHpCeWJBT0IxTU9XWXlXTHI2NUpzZC9YeFB0OU8yK2IybFFPMGRVRW9teHRBd083T3Rkd3hJNk1UYmpmb0puZzJqc2NVQ3JkRCsreUZDT3RjQys1dmlsUUhQcjdiNXp1UysiLCJtYWMiOiJkMjY4ZTk1ZDRkMTI3NjI4ZTdkMmFlNGYzMTQ2ZGJkOTM0N2M3ZmE0NzRiYzg1NTgzMTA3MGQwY2FhNTRjZjQ3IiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6IjN3YTBuNjZvOENDNElsUXJoaUp3K3c9PSIsInZhbHVlIjoidlE3NEhMeVpPdFJmdEZQVjJ3dlJCL2tEdWF4OHFPSHpCeWJBT0IxTU9XWXlXTHI2NUpzZC9YeFB" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "M1ETwM6Tpj0fmyTydedoPUxO4LCZHIs3k3w6LP2q" "uc_cart_id" => "11ca9b4b539f6763917dd6bdceab6ff5" "_previous" => array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/1497" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-25 08:42:03GET/chapter/1497112193