Tuberculosis: A Clinical Practice Guide

Tuberculosis Global Epidemiology

Author(s): Rafael Laniado-Laborín

Pp: 1-6 (6)

DOI: 10.2174/9789811488511120010004

* (Excluding Mailing and Handling)

Abstract

Globally, tuberculosis is one of the top 10 overall causes of death, the leading cause of death from a single infectious agent, and the principal cause of death among subjects living with human immunodeficiency virus infection.

The United Nations and the World Health Organization (WHO) have set very ambitious goals for the period 2020-2035 that include a 95% reduction in the number of deaths and a 90% reduction in TB incidence by 2035 compared with 2015.

The WHO reported in 2018, an estimated 10 million incident cases of TB (global incidence rate: 133 cases per 105 population), and 1.2 million TB deaths, for a case fatality rate of 15.7%. Incidence rates vary widely among regions of the world; geographically, most TB cases in 2018 were in the WHO regions of South-East Asia (44%), Africa (24%) and the Western Pacific (18%).

Rifampin-resistant (RR-TB) or multidrug-resistant TB (MDR-TB) in 2018 occurred in an estimated half a million cases, and accounted for 3.4% of all new cases and 18% of previously treated cases; an estimated 230,000 persons died of either RR or MDR-TB (case fatality rate: 41%).

Almost a quarter of the world population (1.7 billion people or 23%) are estimated to have latent TB infection and therefore are at risk of developing active TB during their lifetime.

Progress toward global TB elimination during 2018 was very modest, as it has occurred in recent years, and if kept at this current pace, the global targets for the period 2020- 2035 will not be accomplished.


Keywords: Epidemiology, Incidence, MDR-TB, Mortality, Tuberculosis, XDRTB.

Related Journals
Related Books
© 2025 Bentham Science Publishers | Privacy Policy
Request history8.2.27PHP Version216msRequest Duration26MBMemory UsageGET chapter/{id}/{param?}Route
  • warninglog[06:25:48] LOG.warning: Optional parameter $id declared before required parameter $request is implic...
  • Booting (115ms)time
  • Application (101ms)time
  • 1 x Booting (53.32%)
    115ms
    1 x Application (46.68%)
    101ms
    12 templates were rendered
    • ebook.chapter_detailschapter_details.blade.php#?blade
    • layouts.chapter_header_sectionchapter_header_section.blade.php#?blade
    • ebook.chapter_top_bannerchapter_top_banner.blade.php#?blade
    • ebook.chapter_bottom_bannerchapter_bottom_banner.blade.php#?blade
    • ebook.ebook_right_bannerebook_right_banner.blade.php#?blade
    • includes.inc_related_journalsinc_related_journals.blade.php#?blade
    • includes.inc_related_ebooksinc_related_ebooks.blade.php#?blade
    • layouts.appapp.blade.php#?blade
    • layouts._login_access_login_access.blade.php#?blade
    • layouts._header_header.blade.php#?blade
    • layouts._main_menu_main_menu.blade.php#?blade
    • layouts._footer_menu_footer_menu.blade.php#?blade
    uri
    GET chapter/{id}/{param?}
    middleware
    web, check_user_access
    controller
    App\Http\Controllers\ChapterController@GetChapterDetails
    namespace
    App\Http\Controllers
    where
    as
    chapter
    file
    app/Http/Controllers/ChapterController.php:1350-1704
    19 statements were executed27.55ms
    • Connection Establishedalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 9. middleware::check_user_access:24
      • 10. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 11. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address (ip_address,visitor_agent,visitor_count, created_on,updated_on) VALUES ('316303896','',1,1740551148,1740551148) ON DUPLICATE KEY UPDATE visitor_count=visitor_count + 1, updated_on=1740551148
      960μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#24
      Backtrace
      • 11. middleware::check_user_access:24
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • INSERT INTO visitor_ip_address_detail (ip_address,visitor_url,visitor_count, created_on,updated_on) VALUES ('316303896','/chapter/14363',1,1740551148,1740551148)
      200μsalphaeurekaselec_live_10_06_2022UserAccessCheck.php#27
      Backtrace
      • 11. middleware::check_user_access:27
      • 12. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 14. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 15. vendor/laravel/framework/src/Illuminate/Foundation/Http/Middleware/VerifyCsrfToken.php:88
    • (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_trail WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_corporate WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_journal_volume_token WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_trail WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_corporate WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_ebook_volume_token WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_trail WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_corporate WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_issue_token WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_trail WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_corporate WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_article_token WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_trail WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_corporate WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_chapter_token WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) union (select `user_id`, `to_ip`, `from_ip` from (select user_id, to_ip, from_ip FROM user_access_disease_corporate WHERE to_ip >= 316303896 ORDER BY to_ip ASC LIMIT 1) as `tjv` where `from_ip` <= 316303896) limit 1
      12.07msalphaeurekaselec_live_10_06_2022UserAccess.php#784
      Bindings
      • 0: 316303896
      • 1: 316303896
      • 2: 316303896
      • 3: 316303896
      • 4: 316303896
      • 5: 316303896
      • 6: 316303896
      • 7: 316303896
      • 8: 316303896
      • 9: 316303896
      • 10: 316303896
      • 11: 316303896
      • 12: 316303896
      • 13: 316303896
      • 14: 316303896
      • 15: 316303896
      Backtrace
      • 14. app/Models/UserAccess/UserAccess.php:784
      • 15. middleware::check_user_access:114
      • 16. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Middleware/SubstituteBindings.php:50
      • 18. vendor/laravel/framework/src/Illuminate/Pipeline/Pipeline.php:183
    • select * from `chapter` where `chapter_id` = '14363' limit 1
      250μsalphaeurekaselec_live_10_06_2022ChapterController.php#1406
      Bindings
      • 0: 14363
      Backtrace
      • 16. app/Http/Controllers/ChapterController.php:1406
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select CONCAT_WS(' ',au.first_name, ' ', ifnull(au.initials,''), ' ', au.last_name) as authors, CONCAT(au.last_name, IFNULL(CONCAT(' ', au.initials), ''), ' ', au.first_name) AS authorsRIS, CONCAT_WS(' ',au.last_name, ' ', ifnull(au.initials,''), ' ', au.first_name) as authorsCiteAs, CONCAT_WS(' ',au.first_name, IFNULL(CONCAT(' ', au.initials), ''), IFNULL(CONCAT(' ', au.last_name), '')) as authorsmodal , `au`.*, `af`.`ror_id`, `af`.`institution`, `af`.`department`, `af`.`country`, `af`.`city`, `af`.`address`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.institution,','),''), ifnull(concat(af.department,','),''), ifnull(concat(af.address,','),''), ifnull(concat(af.city,','),''), ifnull(concat(af.country,','),''), ifnull(concat(af.postal_code,','),''), ifnull(concat(af.phone,','),''), ifnull(concat(af.fax,','),''))) SEPARATOR '|')) as `author_affiliation`, (GROUP_CONCAT(TRIM(BOTH ', ' FROM CONCAT(ifnull(concat(af.web_view,','),''))) SEPARATOR '|')) as `web_view` from `author` as `au` left join `author_affiliation` as `af` on `au`.`author_id` = `af`.`author_id` where `au`.`chapter_id` = '14363' group by `au`.`author_id` order by `au`.`article_id` asc, `au`.`sequence` asc
      1.87msalphaeurekaselec_live_10_06_2022Author.php#86
      Bindings
      • 0: 14363
      Backtrace
      • 13. app/Models/Author.php:86
      • 14. app/Http/Controllers/ChapterController.php:1411
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select * from `keywords` where `chapter_id` = '14363'
      1.25msalphaeurekaselec_live_10_06_2022ChapterController.php#1415
      Bindings
      • 0: 14363
      Backtrace
      • 15. app/Http/Controllers/ChapterController.php:1415
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select * from `ebook` where `ebook_id` = 838 limit 1
      290μsalphaeurekaselec_live_10_06_2022ChapterController.php#1430
      Bindings
      • 0: 838
      Backtrace
      • 16. app/Http/Controllers/ChapterController.php:1430
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 18. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 19. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:206
    • select count(*) as aggregate from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `e`.`ebook_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=838) and se.ebook_id!=838 and v.ebook_status='1'
      3.66msalphaeurekaselec_live_10_06_2022Subject.php#238
      Backtrace
      • 16. app/Models/Subject.php:238
      • 17. app/Http/Controllers/ChapterController.php:1434
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select distinct v.nid as volume_id,e.nid,e.title,v.issn,v.eissn,v.isbn,v.eisbn,e.ebook_id, v.image_file_name,v.file_path,v.flyer_link,v.ebook_volume_id, v.volume_name,v.doi,v.year_id,v.introduction from `subject_ebook` as `se` inner join `ebook` as `e` on `e`.`ebook_id` = `se`.`ebook_id` inner join `ebook_volume` as `v` on `v`.`ebook_id` = `e`.`ebook_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=838) and se.ebook_id!=838 and v.ebook_status='1' limit 10 offset 0
      770μsalphaeurekaselec_live_10_06_2022Subject.php#238
      Backtrace
      • 14. app/Models/Subject.php:238
      • 15. app/Http/Controllers/ChapterController.php:1434
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as aggregate from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=838)
      420μsalphaeurekaselec_live_10_06_2022Subject.php#255
      Backtrace
      • 16. app/Models/Subject.php:255
      • 17. app/Http/Controllers/ChapterController.php:1435
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 19. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 20. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select distinct j.nid as journal_nid,j.title,j.subtitle,j.issn,j.eissn,j.keyword,sj.journal_id,j.image_file_name,j.flyer_link from `subject_journal` as `sj` inner join `journal` as `j` on `j`.`journal_id` = `sj`.`journal_id` where subject_id IN (select subject_id FROM subject_ebook WHERE ebook_id=838) limit 10 offset 0
      590μsalphaeurekaselec_live_10_06_2022Subject.php#255
      Backtrace
      • 14. app/Models/Subject.php:255
      • 15. app/Http/Controllers/ChapterController.php:1435
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select `e`.*, `a`.*, `y`.`year`, `e`.`ebook_volume_id` as `ebook_volume_id`, `a`.`ebook_volume_id` as `ebk_vol_id`, `e`.`ebook_id` as `ebk_ebook_id` from `ebook_volume` as `e` left join `author` as `a` on `e`.`ebook_volume_id` = `a`.`ebook_volume_id` left join `year` as `y` on `y`.`id` = `e`.`year_id` where `e`.`ebook_volume_id` = 2923 and `e`.`is_uploaded` = 1
      650μsalphaeurekaselec_live_10_06_2022EbookVolume.php#271
      Bindings
      • 0: 2923
      • 1: 1
      Backtrace
      • 13. app/Models/EbookVolume.php:271
      • 14. app/Http/Controllers/ChapterController.php:1438
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) rcd from `ebook_volume` where `ebook_id` = 838 and ebook_volume_id <> 2923 limit 1
      340μsalphaeurekaselec_live_10_06_2022EbookVolume.php#999
      Bindings
      • 0: 838
      Backtrace
      • 14. app/Models/EbookVolume.php:999
      • 15. app/Http/Controllers/ChapterController.php:1462
      • 16. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 17. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 18. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from ebook_access where content_type_id = '14363' and content_type = 'c' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      400μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1465
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select count(*) as total_count, content_type_access_id as access_type from ebook_access where content_type_id = '2923' and content_type = 'v' and ( (from_date <= CURDATE() and to_date >= CURDATE() and perpetual= 0) or (from_date is null and to_date is null and perpetual= 1) )
      360μsalphaeurekaselec_live_10_06_2022ContentAccess.php#647
      Backtrace
      • 11. app/Models/ContentAccess.php:647
      • 12. app/Http/Controllers/ChapterController.php:1478
      • 13. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 14. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316303896 and j.to_ip >=316303896 )) and ((j.from_date <= 1740551148 and j.to_date >= 1740551148 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2923) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316303896 and j.to_ip >=316303896 )) and ((j.from_date <= 1740551148 and j.to_date >= 1740551148 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2923) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"ebook_volume" as access_level,"" as chapter_id from `user_access_ebook_volume_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316303896 and j.to_ip >=316303896 )) and ((j.from_date <= 1740551148 and j.to_date >= 1740551148 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.volume_id = 2923)
      930μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1518
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Trial Access" as access_base_text, CASE j.type WHEN 111 THEN true ELSE false END as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_trail` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316303896 and j.to_ip >=316303896 )) and ((j.from_date <= 1740551148 and j.to_date >= 1740551148 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 14363) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Subscribed" as access_base_text, false as terms_popup, "S" as content_download_type, null as restricted_user_access_key, null as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_corporate` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316303896 and j.to_ip >=316303896 )) and ((j.from_date <= 1740551148 and j.to_date >= 1740551148 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 14363) union (select j.user_access_id,j.volume_id,j.user_id,j.from_ip,j.to_ip,j.type,j.track,"Token Based Access" as access_base_text, false as terms_popup, "R" as content_download_type, j.uc_id as restricted_user_access_key, "v" as restricted_user_access_type, CASE j.track WHEN 0 THEN false ELSE true END as tracksAccessByVolume,"chapter" as access_level, j.chapter_id from `user_access_chapter_token` as `j` inner join `user_access_info` as `info` on `j`.`user_access_id` = `info`.`user_access_id` where ((j.from_ip <= 316303896 and j.to_ip >=316303896 )) and ((j.from_date <= 1740551148 and j.to_date >= 1740551148 and j.perpetual= 0) or (j.from_date is null and j.to_date is null and j.perpetual= 1)) and j.chapter_id = 14363)
      790μsalphaeurekaselec_live_10_06_2022UserAccess.php#1266
      Backtrace
      • 13. app/Models/UserAccess/UserAccess.php:1266
      • 14. app/Http/Controllers/ChapterController.php:1549
      • 15. vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • 16. vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
      • 17. vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
    • select b.banner_link, b.banner_name, b.banner_script, b.banner_remarks, b.banner_file_name, b.banner_placement, bd.content_type, bd.content_id from `tbl_banner` as `b` inner join `tbl_banner_detail` as `bd` on `bd`.`banner_id` = `b`.`banner_id` inner join `users` as `u` on `u`.`id` = `b`.`updated_by` where `b`.`banner_ebook` = 1 and `bd`.`content_type` = 'B' and `bd`.`content_id` = 2923 and `b`.`banner_from_date` <= 1740551148 and `b`.`banner_to_date` >= 1740551148 and `b`.`banner_status` = 'A' order by `b`.`banner_id` desc
      1.48msalphaeurekaselec_live_10_06_2022Banner.php#95
      Bindings
      • 0: 1
      • 1: B
      • 2: 2923
      • 3: 1740551148
      • 4: 1740551148
      • 5: A
      Backtrace
      • 13. app/Models/Banner.php:95
      • 14. app/Http/helpers.php:404
      • 17. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 18. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    • select count(*) as aggregate from `uc_cart_products` where cart_id='a326930c50f956469b6960ecfbc61b4e'
      270μsalphaeurekaselec_live_10_06_2022Cart.php#271
      Backtrace
      • 15. app/Models/Cart.php:271
      • 16. view::layouts._header:260
      • 18. vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • 19. vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • 20. vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:73
    App\Models\Keywords
    6Keywords.php#?
    App\Models\Chapter
    1Chapter.php#?
    App\Models\Ebook
    1Ebook.php#?
        _token
        v1TfPTdPaFIP2OxEn0ATVHsHQdKILR7OxfjbhZX6
        uc_cart_id
        a326930c50f956469b6960ecfbc61b4e
        _previous
        array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/14363" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        PHPDEBUGBAR_STACK_DATA
        []
        path_info
        /chapter/14363
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:17 [ "x-https" => array:1 [ 0 => "1" ] "host" => array:1 [ 0 => "alpha.eurekaselect.com" ] "priority" => array:1 [ 0 => "u=0, i" ] "cookie" => array:1 [ 0 => "wayfindertarget=eyJpdiI6InRzSHZTTFdBQ01tM05RbWU5ZFFNaUE9PSIsInZhbHVlIjoiUmlzQmRFT0NFelpZd2gvS1lhcDVPclhxKzdYMUVWcXJBSkRPeTVVMkg0bz0iLCJtYWMiOiIzNzkwYTNlMWE5YTlhNGMyZjRlNmIyMDZlNzM0NDIzMmVhMDhiMWFhYTY5MWJhMTdmN2Y4NWYzODkxOTBhNGNkIiwidGFnIjoiIn0%3Dwayfindertarget=eyJpdiI6InRzSHZTTFdBQ01tM05RbWU5ZFFNaUE9PSIsInZhbHVlIjoiUmlzQmRFT0NFelpZd2gvS1lhcDVPclhxKzdYMUVWcXJBSkRPeTVVMkg0bz0iLCJtYWMiOiIzNzkwYTNlMWE5YTlh" ] "accept-encoding" => array:1 [ 0 => "gzip, deflate, br, zstd" ] "sec-fetch-dest" => array:1 [ 0 => "document" ] "sec-fetch-user" => array:1 [ 0 => "?1" ] "sec-fetch-mode" => array:1 [ 0 => "navigate" ] "sec-fetch-site" => array:1 [ 0 => "none" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "sec-ch-ua-platform" => array:1 [ 0 => ""Windows"" ] "sec-ch-ua-mobile" => array:1 [ 0 => "?0" ] "sec-ch-ua" => array:1 [ 0 => ""HeadlessChrome";v="129", "Not=A?Brand";v="8", "Chromium";v="129"" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] ]
        request_cookies
        0 of 0
        array:1 [ "wayfindertarget" => null ]
        response_headers
        0 of 0
        array:5 [ "content-type" => array:1 [ 0 => "text/html; charset=UTF-8" ] "cache-control" => array:1 [ 0 => "no-cache, private" ] "date" => array:1 [ 0 => "Wed, 26 Feb 2025 06:25:48 GMT" ] "set-cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IjhMMi80OVAybW9wSzdhWmRmUllKSnc9PSIsInZhbHVlIjoiemlhaHlvaDhidWJGbVJCN3JZK2paQ3dIMXBWOUlWMjBQMjAzWmNGRTNTZ0x3S3BFK3JoQUs4ckU1Zjg0QysxQzMwdGZKeHlMc01LcVFHUlNCWXZtMWdZZEJGYTRNVkZXOFlwWGtYOXBxTk5idDhPT2t6SjhGS2VGbUozMk9ISUkiLCJtYWMiOiJhNzliYTM2MzJlNTg4NmRmOTNkNTQ4ZGZkZjE0ZmJmMTc0Njc3MTNmMzJhN2ZiM2Q1YzhiNDI1YzYzNjA1ZWEwIiwidGFnIjoiIn0%3D; expires=Fri, 28 Feb 2025 18:25:48 GMT; Max-Age=216000; path=/; secure; samesite=laxXSRF-TOKEN=eyJpdiI6IjhMMi80OVAybW9wSzdhWmRmUllKSnc9PSIsInZhbHVlIjoiemlhaHlvaDhidWJGbVJCN3JZK2paQ3dIMXBWOUlWMjBQMjAzWmNGRTNTZ0x3S3BFK3JoQUs4ckU1Zjg0QysxQzMwdGZKe" 1 => "alphaeurekaselectnet_session=eyJpdiI6Ilg5UlVrZXo2REE0RFdCZUVBNHdHZmc9PSIsInZhbHVlIjoid1hKbERDbFoxRXdoM2ZlM3Ryd0pGSDQyNkNBbFU4amNsSUl1ZVlxbStlMGdXckNYclUyMFRURzJwMHVuaGJscW1EN2ZuS01iWE5LeWRUMXllczczTDBlblVLRjZUdGR1N2NiWFgxRkI4bnZFUW5RdG5RNGNIdVRvNTFBMUdXcGgiLCJtYWMiOiI2NjhiNDg2ODE4ODAwNjNjNGJhYjgzYTI1NGUwNGRjYjM5MWQ0ZGJkMGZiYTcyMGZmODc5YjUyNDlmZWJhYjM1IiwidGFnIjoiIn0%3D; path=/; secure; httponly; samesite=laxalphaeurekaselectnet_session=eyJpdiI6Ilg5UlVrZXo2REE0RFdCZUVBNHdHZmc9PSIsInZhbHVlIjoid1hKbERDbFoxRXdoM2ZlM3Ryd0pGSDQyNkNBbFU4amNsSUl1ZVlxbStlMGdXckNYclUyMFRURzJ" ] "Set-Cookie" => array:2 [ 0 => "XSRF-TOKEN=eyJpdiI6IjhMMi80OVAybW9wSzdhWmRmUllKSnc9PSIsInZhbHVlIjoiemlhaHlvaDhidWJGbVJCN3JZK2paQ3dIMXBWOUlWMjBQMjAzWmNGRTNTZ0x3S3BFK3JoQUs4ckU1Zjg0QysxQzMwdGZKeHlMc01LcVFHUlNCWXZtMWdZZEJGYTRNVkZXOFlwWGtYOXBxTk5idDhPT2t6SjhGS2VGbUozMk9ISUkiLCJtYWMiOiJhNzliYTM2MzJlNTg4NmRmOTNkNTQ4ZGZkZjE0ZmJmMTc0Njc3MTNmMzJhN2ZiM2Q1YzhiNDI1YzYzNjA1ZWEwIiwidGFnIjoiIn0%3D; expires=Fri, 28-Feb-2025 18:25:48 GMT; path=/; secureXSRF-TOKEN=eyJpdiI6IjhMMi80OVAybW9wSzdhWmRmUllKSnc9PSIsInZhbHVlIjoiemlhaHlvaDhidWJGbVJCN3JZK2paQ3dIMXBWOUlWMjBQMjAzWmNGRTNTZ0x3S3BFK3JoQUs4ckU1Zjg0QysxQzMwdGZKe" 1 => "alphaeurekaselectnet_session=eyJpdiI6Ilg5UlVrZXo2REE0RFdCZUVBNHdHZmc9PSIsInZhbHVlIjoid1hKbERDbFoxRXdoM2ZlM3Ryd0pGSDQyNkNBbFU4amNsSUl1ZVlxbStlMGdXckNYclUyMFRURzJwMHVuaGJscW1EN2ZuS01iWE5LeWRUMXllczczTDBlblVLRjZUdGR1N2NiWFgxRkI4bnZFUW5RdG5RNGNIdVRvNTFBMUdXcGgiLCJtYWMiOiI2NjhiNDg2ODE4ODAwNjNjNGJhYjgzYTI1NGUwNGRjYjM5MWQ0ZGJkMGZiYTcyMGZmODc5YjUyNDlmZWJhYjM1IiwidGFnIjoiIn0%3D; path=/; secure; httponlyalphaeurekaselectnet_session=eyJpdiI6Ilg5UlVrZXo2REE0RFdCZUVBNHdHZmc9PSIsInZhbHVlIjoid1hKbERDbFoxRXdoM2ZlM3Ryd0pGSDQyNkNBbFU4amNsSUl1ZVlxbStlMGdXckNYclUyMFRURzJ" ] ]
        session_attributes
        0 of 0
        array:5 [ "_token" => "v1TfPTdPaFIP2OxEn0ATVHsHQdKILR7OxfjbhZX6" "uc_cart_id" => "a326930c50f956469b6960ecfbc61b4e" "_previous" => array:1 [ "url" => "https://alpha.eurekaselect.com/chapter/14363" ] "_flash" => array:2 [ "old" => [] "new" => [] ] "PHPDEBUGBAR_STACK_DATA" => [] ]
        ClearShow all
        Date ↕MethodURLData
        #12025-02-26 06:25:48GET/chapter/14363112198