Hypertrophic Cardiomyopathy in Pediatric Population

Pp: 59-83 (25)

* (Excluding Mailing and Handling)

Abstract

Hypertrophic cardiomyopathy (HCM) is an inherited autosomal dominant genetic disease characterised by asymmetrical increased wall thickness of a non-dilated LV chamber. It has a diverse natural history which is attributed to its heterogeneous clinical presentation. HCM could be diagnosed clinically, by ECG changes and definitely by echocardiographic characteristics. Pharmacological therapy has an important role in the management of HCM. Alcohol septal ablation and pacing may be used in certain conditions. Septal myectomy, Morrow procedure, is indicated to reduce persistent gradient and alleviate symptoms refractory to medications.

Keywords: Cardiomyopathy, Congenital Heart Disease, Dual Chamber Pacing, End-Stage Heart Failure, Gene Mutation, Hypertrophy, Myectomy, Morrow, Outflow Obstruction, Septal Ablation, Sudden Cardiac Death.