Abstract
The pathology of osteoarthritis is extremely complex and multifactorial. Recent technological advances have allowed the identification of specific genes and genetic alterations which have helped to elucidate some intricacies involved in the molecular basis of disease development and progression. Known factors and key recent discoveries in pathogenesis, plus typical gross and histologic pathologic findings are described in this chapter.
Keywords: Degenerative joint disease, Gene, Genetic, Gross, Histology, Microscopic, Molecular, Morphology, Osteoarthritis, Pathology.