摘要
约有50％的因溃疡性结肠炎（UC）接受过IPAA手术的患者至少发生1次囊袋炎。囊炎患者具有广泛的症状，内窥镜和组织学特征，病程和预后。迄今为止，就内窥镜检查和组织学而言，尚无公认的诊断标准。但是，已经提出了使用综合评分（例如，Pouchitis Triad，Heidelberg Pouchitis活动评分和Pouchitis疾病活动指数（PDAI））的半客观评估来诊断回肠囊吻合术（IPAA）患者的囊炎。在一项包括4项随机试验的系统评价中，评估了5种药物治疗急性囊炎，环丙沙星与甲硝唑相比在诱导缓解方面更有效。利福昔明并不比安慰剂有效，而布地奈德灌肠剂和甲硝唑在诱导急性眼袋炎缓解方面同样有效。建议每年复发3次以上的囊炎患者应进行维持治疗，指南建议使用环丙沙星或益生菌VSL＃3。在患有抗生素难治性眼袋炎的患者中，应寻求和治疗与抗生素难治性病程相关的继发因素。在这篇综述中，我们将讨论溃疡性结肠炎患者的眼袋炎的预防和管理。
关键词: 眼袋炎，预防，益生菌，抗生素，缓解，药物治疗。
图形摘要
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