[1]
Kolodkin, A.L.; Levengood, D.V.; Rowe, E.G.; Tai, Y.T.; Giger, R.J.; Ginty, D.D. Neuropilin is a semaphorin III receptor. Cell, 1997, 90(4), 753-762.
[2]
Chen, H.; Chédotal, A.; He, Z.; Goodman, C.S.; Tessier-Lavigne, M. Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. Neuron, 1997, 19(3), 547-559.
[3]
Gaur, P.; Bielenberg, D.R.; Samuel, S.; Bose, D.; Zhou, Y.; Gray, M.J.; Dallas, N.A.; Fan, F.; Xia, L.; Lu, J.; Ellis, L.M. Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis. Clin. Cancer Res., 2009, 15(22), 6763-6770.
[4]
Grandclement, C.; Borg, C. Neuropilins: A new target for cancer therapy. Cancers (Basel), 2011, 3(2), 1899-1928.
[5]
Winberg, M.L.; Noordermeer, J.N.; Tamagnone, L.; Comoglio, P.M.; Spriggs, M.K.; Tessier-Lavigne, M.; Goodman, C.S. Plexin A is a neuronal semaphorin receptor that controls axon guidance. Cell, 1998, 95(7), 903-916.
[6]
Takahashi, T.; Fournier, A.; Nakamura, F.; Wang, L.H.; Murakami, Y.; Kalb, R.G.; Fujisawa, H.; Strittmatter, S.M. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell, 1999, 99(1), 59-69.
[7]
He, Z.; Tessier-Lavigne, M. Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell, 1997, 90(4), 739-751.
[8]
Staton, C.A.; Kumar, I.; Reed, M.W.; Brown, N.J. Neuropilins in physiological and pathological angiogenesis. J. Pathol., 2007, 212(3), 237-248.
[9]
Kärpänen, T.; Heckman, C.A.; Keskitalo, S.; Jeltsch, M.; Ollila, H.; Neufeld, G.; Tamagnone, L.; Alitalo, K. Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J., 2006, 20(9), 1462-1472.
[10]
Goel, H.L.; Mercurio, A.M. VEGF targets the tumour cell. Nat. Rev. Cancer, 2013, 13(12), 871-882.
[11]
Glinka, Y.; Stoilova, S.; Mohammed, N.; Prud’homme, G.J. Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta. Carcinogenesis, 2011, 32(4), 613-621.
[12]
Nasarre, P.; Gemmill, R.M.; Potiron, V.A.; Roche, J.; Lu, X.; Barón, A.E.; Korch, C.; Garrett-Mayer, E.; Lagana, A.; Howe, P.H.; Drabkin, H.A. Neuropilin-2 Is upregulated in lung cancer cells during TGF-β1-induced epithelial-mesenchymal transition. Cancer Res., 2013, 73(23), 7111-7121.
[13]
Evans, I.M.; Yamaji, M.; Britton, G.; Pellet-Many, C.; Lockie, C.; Zachary, I.C.; Frankel, P. Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells. Mol. Cell. Biol., 2011, 31(6), 1174-1185.
[14]
Banerjee, S.; Sengupta, K.; Dhar, K.; Mehta, S.; D’Amore, P.A.; Dhar, G.; Banerjee, S.K. Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1. Mol. Carcinog., 2006, 45(11), 871-880.
[15]
Stępka, K.; Wierzbowska, A. Neuropilins - structure, function, role in cancerogenesis. Acta Haematol. Pol., 2015, 46(5), 339-346.
[16]
Ellis, L.M. The role of neuropilins in cancer. Mol. Cancer Ther., 2006, 5(5), 1099-1107.
[17]
Yamagata, M.; Herman, J.P.; Sanes, J.R. Lamina-specific expression of adhesion molecules in developing chick optic tectum. J. Neurosci., 1995, 15(6), 4556-4571.
[18]
Jubb, A.M.; Strickland, L.A.; Liu, S.D.; Mak, J.; Schmidt, M.; Koeppen, H. Neuropilin-1 expression in cancer and development. J. Pathol., 2012, 226(1), 50-60.
[19]
Jubb, A.M.; Sa, S.M.; Ratti, N.; Strickland, L.A.; Schmidt, M.; Callahan, C.A.; Koeppen, H. Neuropilin-2 expression in cancer. Histopathology, 2012, 61(3), 340-349.
[20]
Hansen, W.; Hutzler, M.; Abel, S.; Alter, C.; Stockmann, C.; Kliche, S.; Albert, J.; Sparwasser, T.; Sakaguchi, S.; Westendorf, A.M.; Schadendorf, D.; Buer, J.; Helfrich, I. Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth. J. Exp. Med., 2012, 209(11), 2001-2016.
[21]
Yaqoob, U.; Cao, S.; Shergill, U.; Jagavelu, K.; Geng, Z.; Yin, M.; de Assuncao, T.M.; Cao, Y.; Szabolcs, A.; Thorgeirsson, S.; Schwartz, M.; Yang, J.D.; Ehman, R.; Roberts, L.; Mukhopadhyay, D.; Shah, V.H. Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment. Cancer Res., 2012, 72(16), 4047-4059.
[22]
Kim, W.H.; Lee, S.H.; Jung, M.H.; Seo, J.H.; Kim, J.; Kim, M.A.; Lee, Y.M. Neuropilin2 expressed in gastric cancer endothelial cells increases the proliferation and migration of endothelial cells in response to VEGF. Exp. Cell Res., 2009, 315(13), 2154-2164.
[23]
Kölbl, A.C.; Birk, A.E.; Kuhn, C.; Jeschke, U.; Andergassen, U. Influence of VEGFR and LHCGR on endometrial adenocarcinoma. Oncol. Lett., 2016, 12(3), 2092-2098.
[24]
Trimble, C.L.; Method, M.; Leitao, M.; Lu, K.; Ioffe, O.; Hampton, M.; Higgins, R.; Zaino, R.; Mutter, G.L. Management of endometrial precancers. Obstet. Gynecol., 2012, 120(5), 1160-1175.
[25]
Opławski, M.; Michalski, M.; Witek, A.; Michalski, B.; Zmarzły, N.; Jęda-Golonka, A.; Styblińska, M.; Gola, J.; Kasprzyk-Żyszczyńska, M.; Mazurek, U.; Plewka, A. Identification of a gene expression profile associated with the regulation of angiogenesis in endometrial cancer. Mol. Med. Rep., 2017, 16(3), 2547-2555.
[26]
Goel, H.L.; Mercurio, A.M. Enhancing integrin function by VEGF/ neuropilin signaling: Implications for tumor biology. Cell Adhes. Migr., 2012, 6(6), 554-560.
[27]
Handa, A.; Tokunaga, T.; Tsuchida, T.; Lee, Y.H.; Kijima, H.; Yamazaki, H.; Ueyama, Y.; Fukuda, H.; Nakamura, M. Neuropilin-2 expression affects the increased vascularization and is a prognostic factor in osteosarcoma. Int. J. Oncol., 2000, 17(2), 291-295.
[28]
Kawakami, T.; Tokunaga, T.; Hatanaka, H.; Kijima, H.; Yamazaki, H.; Abe, Y.; Osamura, Y.; Inoue, H.; Ueyama, Y.; Nakamura, M. Neuropilin 1 and neuropilin 2 co-expression is significantly correlated with increased vascularity and poor prognosis in nonsmall cell lung carcinoma. Cancer, 2002, 95(10), 2196-2201.
[29]
Yasuoka, H.; Kodama, R.; Tsujimoto, M.; Yoshidome, K.; Akamatsu, H.; Nakahara, M.; Inagaki, M.; Sanke, T.; Nakamura, Y. Neuropilin-2 expression in breast cancer: Correlation with lymph node metastasis, poor prognosis, and regulation of CXCR4 expression. BMC Cancer, 2009, 9, 220.
[30]
Miao, H.Q.; Klagsbrun, M. Neuropilin is a mediator of angiogenesis. Cancer Metastasis Rev., 2000, 19(1-2), 29-37.
[31]
Neufeld, G.; Kessler, O.; Herzog, Y. The interaction of Neuropilin-1 and Neuropilin-2 with tyrosine-kinase receptors for VEGF. Adv. Exp. Med. Biol., 2002, 515, 81-90.
[32]
Takagi, S.; Hirata, T.; Agata, K.; Mochii, M.; Eguchi, G.; Fujisawa, H. The A5 antigen, a candidate for the neuronal recognition molecule, has homologies to complement components and coagulation factors. Neuron, 1991, 7(2), 295-307.
[33]
Gluzman-Poltorak, Z.; Cohen, T.; Herzog, Y.; Neufeld, G. Neuropilin-2 and neuropilin-1 are receptors for VEGF165 and PLGF-2, but only neuropilin-2 functions as a receptor for VEGF145. J. Biol. Chem., 2000, 275, 18040-18045.
[34]
Goel, H.L.; Chang, C.; Pursell, B.; Leav, I.; Lyle, S.; Xi, H.S.; Hsieh, C.C.; Adisetiyo, H.; Roy-Burman, P.; Coleman, I.M.; Nelson, P.S.; Vessella, R.L.; Davis, R.J.; Plymate, S.R.; Mercurio, A.M. VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer. Cancer Discov., 2012, 2(10), 906-921.
[35]
Nguyen, H.; Ivanova, V.S.; Kavandi, L.; Rodriguez, G.C.; Maxwell, G.L.; Syed, V. Progesterone and 1,25-dihydroxyvitamin D3 inhibit endometrial cancer cell growth by upregulating semaphorin 3B and semaphorin 3F. Mol. Cancer Res., 2011, 9(11), 1479-1492.
[36]
Straume, O.; Akslen, L.A. Increased expression of VEGF-receptors (FLT-1, KDR, NRP-1) and thrombospondin-1 is associated with glomeruloid microvascular proliferation, an aggressive angiogenic phenotype, in malignant melanoma. Angiogenesis, 2003, 6(4), 295-301.
[37]
Okon, I.S.; Ding, Y.; Coughlan, K.A.; Wang, O.; Song, P.; Benbrook, D.M.; Zou, M. Aberrant NRP-1 expression serves as predicator of metastatic endometrial and lung cancers Logo of oncotarget. Oncotarget, 2016, 7(7), 7970-7978.
[38]
Bednarek, W.; Mazurek-Kociubowska, M.; Sobstyl, M.; Wertel, I.; Czekierdowski, A. Expression of lymphangiogenesis marker neuropilin-1 in different types of ovarian cancer. Ginekol. Pol., 2010, 81(3), 176-182.
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