Abstract
Background: Nanocarriers have been a part of drug delivery for some decades now. Due to the enormous advantages offered by them, they are replacing the conventionally available systems.
Objective: The objective of the current review is to focus wider applications of these nanocarriers in drug delivery, diagnosis, imaging, and targeting as well. It also focuses on the different types of nanocarriers, method of preparation, characterization and most advanced uses or application in medicine.
Methods: Literature has been reviewed intensely. Data from various sources like NCBI PubMed and other valued journals have been reviewed thoroughly. Various research investigations related to nanocarriers systems have been compiled.
Results: Selection of the nanocarriers type as well as their composition depends upon the disease and the application for which it is to be used. Nanocarriers have been investigated for various diseases such as cancer drug delivery, cardiovascular drug delivery, insulin delivery, antimalarial drug delivery, central nervous system drug delivery, ophthalmic, pulmonary and brain delivery, etc.
Conclusion: Nanotherapy has led to the advancement in the delivery of chemotherapeutic drugs in cancer because of their characteristic enhanced permeation and retention in the tumor tissue. Also, its applications in various other aspects of therapeutics have been extraordinary and much more is yet to be explored.
Keywords: Nanotechnology, nanocarriers, nanotherapy, cancer drug delivery, cardiovascular, chemotherapeutic.
Graphical Abstract