Gene Regulation in Cancer Gene Therapy Strategies

Ian      Scanlon; Panos      Lehouritis; Ion      Niculescu-Duvaz; Richard      Marais; Caroline   J.   Springer

doi:10.2174/0929867033456837

Abstract

Regulation of expression in gene therapy is considered to be a very desirable goal, preventing toxic effects and improving biological efficacy. A variety of systems have been reported in an ever widening range of applications, this paper describes these systems with specific reference to cancer gene therapy.

Keywords: transcriptional control, regulated expression, gdept, suicide gene

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