摘要
纳米医学的一个新兴焦点是探索多功能纳米复合材料,这些材料整合了刺激响应,治疗和/或诊断功能。 在这项努力中,富含半胱氨酸的蛋白质由于其良好的生物降解性,生物相容性和易于化学修饰而作为通用平台引起了相当大的关注。 本综述调查了富含半胱氨酸蛋白质的生物医学材料,包括蛋白质 - 金属纳米复合物,金纳米粒子 - 蛋白质聚集体,蛋白质基纳米粒子和水凝胶,重点是它们的制备方法,特别是基于半胱氨酸残基相关反应的那些。。 他们强调了它们在肿瘤靶向给药和诊断中的应用。
关键词: 富含半胱氨酸的蛋白质,药物输送,癌症诊断,基于蛋白质的纳米颗粒,水凝胶,生物医学材料。
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