摘要
心房颤动是临床实践中遇到的最常见的节律紊乱。尽管通常认为其本质上仅是心律失常，但目前的证据表明心房肌病既是心房颤动的基质又是心房颤动的结果，从而引发恶性的，自我延续的循环。这种肌病是由心房组织的压力诱导（包括压力/容量超负荷，炎症，氧化应激）反应引发的，这种反应从长远来看变得适应不良，并且结合了结构，特别是纤维化和电重构的元素，与现代方法相结合产生这些过程的潜在有用的生物标志物。生物标志物值变得更大，因为它们都可以预测心房颤动的发生和治疗结果。这篇小型综述将重点关注人体研究中已经验证的心房重塑（电学和结构）和纤维化的生物标志物，包括生化，组织学和成像方法。
关键词: 心房颤动，生物标志物，结构重塑，纤维化，电重构，胶原肽，高级糖基化终产物，miRNA。
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